Tumor angiogenesis and microcirculation /
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| Imprint: | New York : Dekker, c2001. |
|---|---|
| Description: | xvi, 623 p. : ill. ; 24 cm. |
| Language: | English |
| Series: | Basic and clinical oncology ; 24 |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4469314 |
Table of Contents:
- Series Introduction
- Preface
- Contributors
- I. Biological Principles of Angiogenesis
- 1. Endothelial Cells and Pericytes in Tumor Vasculature
- 2. The Extracellular Matrix and the Regulation of Angiogenesis
- 3. Matrix Metalloproteinases (Matrixins) and Their Inhibitors (TIMPS) in Angiogenesis
- 4. Regulation of Cell Migration in the Process of Angiogenesis
- 5. Plasmin, Plasmin Inhibitors, and Angiogenesis
- II. Assays to Study Angiogenesis
- 6. Assays to Study Angiogenesis
- 7. Screening for Angiogenesis Inhibitors with the Chick Chorioallantoic Membrane and the Mouse Corneal Micropocket Assays
- 8. Capillary Morphogenesis In Vitro: Cytokine Interactions and Balanced Proteolysis
- 9. Skin Fold Chamber Models
- 10. Protease Assays and Their Use in the Discovery of Novel Regulators of Angiogenesis
- III. Angiogenic Factors
- 11. Vascular Endothelial Growth Factor/Vascular Permeability Factor: Multiple Biological Activities for Promoting Angiogenesis
- 12. Tie Receptors, Ang Ligands
- 13. Vascular Endothelial Growth Factor Receptors
- 14. Regulation of Vascular Endothelial Growth Factor (VEGF) Expression
- 15. Fibroblast Growth Factors
- 16. Role of Proangiogenic Cytokines and Inhibitors of Neovascularization in Tumor Angiogenesis
- IV. Regulation of Angiogenesis
- 17. The Link Between Oncogenes, Signal Transduction Therapy, and Tumor Angiogenesis
- 18. Genetic Control of Angiogenesis by Tumor Suppressor Genes
- 19. Regulation of Neoplastic Angiogenesis by the Organ Microenvironment
- 20. Role of Macrophages in Tumor Angiogenesis
- 21. Phenotypic Analysis of Endothelium from the Tumor Vasculature
- V. Angiogenesis Inhibitors: Preclinical and Clinical Drugs
- 22. Drug Delivery and Angiogenesis Inhibition in the Treatment of Brain Tumors
- 23. Matrix-Associated Endogenous Inhibitors of Angiogenesis
- 24. [alpha]v[beta]3 and Its Antagonists in the Control of Angiogenesis
- 25. The Role of Vascular Endothelial Growth Factor in Angiogenesis
- 26. TNP-470: Preclinical and Clinical Development
- 27. Matrix Metalloproteinase Inhibitors
- 28. Tumoral Vascularity: What Does It Tell Us About the Growth and Spread of Cancer?
- 29. The Prognostic and Diagnostic Value of Circulating Angiogenic Factors in Cancer Patients
- VI. Future Perspectives
- 30. Perspectives in Vascular Cancer Therapy: An Introduction
- 31. The Combination of Antiangiogenic Therapy with Cytotoxic Therapy: A Systems Approach
- 32. Targeting the Vasculature of Solid Tumors
- 33. Combining Antivascular Approaches with Radiotherapy: A Perspective
- 34. Antiangiogenic Gene Therapy
- Index
