Handbook of statistics in clinical oncology /
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| Imprint: | New York : Dekker, c2001. |
|---|---|
| Description: | xiv, 548 p. : ill. ; 24 cm. |
| Language: | English |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4478495 |
Table of Contents:
- Preface
- Contributors
- Phase I. Trials
- 1.. Overview of Phase I Trials
- 2.. Dose-Finding Designs Using Continual Reassessment Method
- 3.. Choosing a Phase I Design
- Phase II. Trials
- 4.. Overview of Phase II Clinical Trials
- 5.. Designs Based on Toxicity and Response
- 6.. Phase II Selection Designs
- Phase III. Trials
- 7.. Power and Sample Size for Phase III Clinical Trials of Survival
- 8.. Multiple Treatment Trials
- 9.. Factorial Designs with Time-to-Event End Points
- 10.. Therapeutic Equivalence Trials
- 11.. Early Stopping of Cancer Clinical Trials
- 12.. Use of the Triangular Test in Sequential Clinical Trials
- Complementary Outcomes
- 13.. Design and Analysis Considerations for Complementary Outcomes
- 14.. Health-Related Quality-of-Life Outcomes
- 15.. Statistical Analysis of Quality of Life
- 16.. Economic Analysis of Cancer Clinical Trials
- Prognostic Factors and Exploratory Analysis
- 17.. Prognostic Factor Studies
- 18.. Statistical Methods to Identify Prognostic Factors
- 19.. Explained Variation in Proportional Hazards Regression
- 20.. Graphical Methods for Evaluating Covariate Effects in the Cox Model
- 21.. Graphical Approaches to Exploring the Effects of Prognostic Factors on Survival
- 22.. Tree-Based Methods for Prognostic Stratification
- Interpreting Clinical Trials
- 23.. Problems in Interpreting Clinical Trials
- 24.. Commonly Misused Approaches in the Analysis of Cancer Clinical Trials
- 25.. Dose-Intensity Analysis
- 26.. Why Kaplan-Meier Fails and Cumulative Incidence Succeeds When Estimating Failure Probabilities in the Presence of Competing Risks
- 27.. Meta-Analysis
- Index
