Meningococcal vaccines : methods and protocols /
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| Imprint: | Totowa, N.J. : Humana Press, c2001. |
|---|---|
| Description: | xvii, 421 p. : ill. ; 24 cm. |
| Language: | English |
| Series: | Methods in molecular medicine ; 66 |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4486708 |
Table of Contents:
- Foreword
- Preface
- Contributors
- 1. Meningococcal Vaccines and Vaccine Developments
- 2. Immune Response and Host-Pathogen Interactions
- 3. Purification of Capsular Polysaccharide
- 4. Protein-Polysaccharide Conjugation
- 5. N-Propionylation
- 6. Outer Membrane Protein Purification
- 7. Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease
- 8. Methods for Manipulation of Transferrin-Binding Proteins
- 9. Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens Derived from N. meningitidis Outer Membrane Proteins
- 10. Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetics
- 11. Construction of porA Mutants
- 12. Construction of LPS Mutants
- 13. Recombinant Proteins in Vaccine Development
- 14. Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries
- 15. Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity
- 16. Early Experiences with Nasal Vaccines against Meningococcal Disease
- 17. Animal Models for Meningococcal Disease
- 18. Determination of Antibody Responses to Meningococcal Antigens by ELISA
- 19. Immunoblot Analysis of Sera from Patients and Vaccinees
- 20. Serogroup B and C Serum Bactericidal Assays
- 21. A Modified ELISA for Measurement of High-Avidity lgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers
- 22. Whole-Blood Model
- 23. Antibody-Induced Opsonophagocytosis of Serogroup B Meningococci Measured by Flow Cytometry
- 24. T-Cell Responses Against Meningococcal Antigens
- 25. CD4 T-Cell Epitope Mapping
- 26. Epitope Mapping
- 27. Meningococcal Vaccine Trials
- 28. The Introduction of Group C Conjugate Meningococcal Vaccine into the UK
- Index
