Textbook of pediatric rheumatology /

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Bibliographic Details
Edition:	4th ed.
Imprint:	Philadelphia : W.B. Saunders, c2001.
Description:	xv, 819 p. : ill. ; 29 cm.
Language:	English
Subject:	Pediatric rheumatology. Rheumatism in children. Rheumatic Diseases -- Child. Arthritis -- Child. Connective Tissue Diseases -- Child. Vasculitis -- Child. Pediatric rheumatology. Rheumatism in children.
Format:	Print Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/4495828

Hidden Bibliographic Details
Other authors / contributors:	Cassidy, James T. Petty, Ross E.
ISBN:	0721681719
Notes:	Includes bibliographical references and index.

Table of Contents:

Contributing Authors
Foreword
Preface
Color Plate Section
Basic Concepts
Chapter 1. Introduction to the Study of Rheumatic Diseases in Children
Evolution of Terminology
The Rheumatic Diseases of Childhood
Emergence of the Specialty of Pediatric Rheumatology
Factors that May Modify Rheumatic Diseases in Children
Childhood Rheumatic Diseases: Extent of the Problem
Advances in Pediatric Rheumatology
References
Chapter 2. Structure and Function
Joints
Articular Cartilage
Synovium
Vascular Supply
Connective Tissue Structures
Skeletal Muscle
References
Chapter 3. The Immune System and the Inflammatory Response
Innate Immunity
Adaptive Immunity
The Multifactorial Origin of Autoimmune Diseases
Mechanisms of Tissue Injury in Autoimmune-Mediated Diseases
The Autonomic Nervous and Endocrine Mediators in Inflammation
References
Chapter 4. Integrative Genomics
The Genome
Monogenic Disease in Pediatric Rheumatology
Complex Genetic Traits
Pediatric Rheumatic Illnesses as Complex Genetic Traits
Functional Genomics
Conclusions
References
Chapter 5. Pharmacology and Drug Therapy
Concepts in Pharmacology
Antirheumatic Drugs
Acknowledgment
References
Chapter 6. Design, Measurement, and Analysis of Clinical Investigations
Evidence-Based Medicine and Clinical Investigation
Definition of Clinical Research
General Terminology and Basic Concepts Associated with Clinical Studies
Epidemiologic and Behavioral Studies
Outcomes and Health Services Research
Patient-Oriented Research
Considerations for Individual Clinical Trials
Understanding and Describing Data
Statistical Tests of Inference Commonly Used in Clinical Investigations
Judging the Quality of a Report of a Clinical Investigation
References
Chapter 7. Assessment of Health Status, Function, and Quality of Life Outcomes: Methodology and Instruments
Background
Process of Instrument Development
Background on Available Instruments for Childhood Rheumatic Diseases
Instruments for Juvenile Rheumatoid Arthritis
Instruments Available for Use in Rheumatic Diseases Other than Juvenile Idiopathic Arthritis
Conclusion
References
Chapter 8. A General Approach to Management of Rheumatic Diseases in Children
Patient Education
Counseling
Adherence (Compliance)
Sibling Issues
School Issues
Transition
Financial Issues
Unconventional Remedies
Physical and Occupational Therapy
Immunization
References
Appendix 8-1
Appendix 8-2
Chronic Arthritis
Chapter 9. Chronic Arthritis in Childhood
Historical Review
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Organ-Specific Manifestations of Chronic Arthritis
Pathology
Laboratory Examination
Radiologic Examination
Treatment
Course of the Disease and Prognosis
Perspective
References
Chapter 10. Polyarthritis
Definitions
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Diagnosis
Pathology
Laboratory Examination
Radiologic Examination
Treatment
Course of the Disease and Prognosis
References
Chapter 11. Oligoarthritis
Definition
Epidemiology
Genetics
Etiology and Pathogenesis
Clinical Manifestations
Diagnosis
Complications: Uveitis
Laboratory Evaluation
Radiographic Evaluation
Management
Disease Course and Prognosis
Perspective
References
Chapter 12. Systemic Arthritis
Definition and Classification
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Diagnosis and Differential Diagnosis
Pathology
Laboratory Examination
Radiologic Examination
Treatment
Course of the Disease and Prognosis
References
Chapter 13. Juvenile Ankylosing Spondylitis
Definition and Classification
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Pathology
Differential Diagnosis
Laboratory Examination
Radiologic Examination
Treatment
Course of the Disease and Prognosis
References
Chapter 14. Psoriatic Arthritis
Definition and Classification
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Pathology
Laboratory Examination
Radiologic Examination
Treatment
Course of the Disease and Prognosis
References
Chapter 15. Arthropathies of Inflammatory Bowel Disease
Definition and Classification
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Pathology
Diagnosis and Laboratory Examination
Radiologic Examination
Treatment
Course of the Disease and Prognosis
References
Systemic Connective Tissue Diseases
Chapter 16. Systemic Lupus Erythematosus
Historical Review
Definition and Classification
Epidemiology
Genetic Background
Etiology and Pathogenesis
Clinical Manifestations
Pathology
Laboratory Examination
General Assessment
Treatment
Management of Specific Aspects of the Disease
Course of the Disease and Prognosis
Drug-Induced Lupus
Perspective
References
Chapter 17. Neonatal Lupus Erythematosus
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations of Neonatal Lupus Erythematosus
Course of the Disease and Prognosis
Animal Models of Neonatal Lupus Erythematosus
References
Chapter 18. Juvenile Dermatomyositis
Historical Review
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Pathology
Differential Diagnosis
Laboratory Examination
Radiologic Examination
Treatment
Course of the Disease and Prognosis
References
Chapter 19. The Systemic Sclerodermas and Related Disorders
Definition and Classification
Historical Review
Diffuse Cutaneous Systemic Scleroderma
Limited Cutaneous Sysetmic Scleroderma
References
Chapter 20. Localized Sclerodermas
Definition and Classification
Epidemiology
Etiology and Pathogenesis
Clinical Manifestations
Pathology
Differential Diagnosis
Laboratory Examination
Treatment
Course of the Disease and Prognosis
References
Chapter 21. Overlap Syndromes
Mixed Connective Tissue Disease
Sjogren's Syndrome
References
Systemic Vasculitis
Chapter 22. Vasculitis and Its Classification
Classification
General Clinical Aspects of Vasculitis
Epidemiology
References
Chapter 23. Leukocytoclastic Vasculitis
Henoch-Schonlein Purpura
Hypersensitivity Angiitis
Hypocomplementemic Urticarial Vasculitis
Mixed Cryoglobulinemia
Other Leukocytoclastic and Perivasculitic Syndromes and Similar Disorders
References
Chapter 24. Polyarteritis Nodosa and Related Vasculitides
Polyarteritis Nodosa
Cutaneous Polyarteritis
Other Rare Vasculitides
References
Chapter 25. Kawasaki Disease
Historical Background
Definition and Diagnostic Criteria
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Differential Diagnosis
Pathology
Laboratory Examination
Treatment
Treatment of Relapses
Follow-up and Monitoring of Cardiac Status
Disease Course and Prognosis
Perspective
References
Chapter 26. Granulomatous Vasculitis, Giant Cell Arteritis and Sarcoidosis
Wegener's Granulomatosis
Giant Cell Arteritis
Sarcoidosis
References
Chapter 27. Behcet's Disease
Definition and Classification
Epidemiology
Genetic Background
Etiology and Pathogenesis
Clinical Manifestations
Pathology
Laboratory Examination
Imaging Studies
Diagnosis
Treatment
Course of the Disease and Prognosis
References
Arthritis Related to Infection
Chapter 28. Infectious Arthritis and Osteomyelitis
Septic Arthritis
Osteomyelitis
Arthritis Caused by Viruses
Arthritis Associated with Other Infections
Postinfectious Arthritis
References
Chapter 29. Lyme Disease
Definition and Classification
Epidemiology
Genetic Background
Etiology and Pathogenesis
Clinical Manifestations
Pathology
Laboratory Examination
Diagnosis
Treatment
Course of the Disease and Prognosis
References
Chapter 30. Reactive Arthritis
Definition
Classification and Diagnostic Criteria
Epidemiology
Genetic Background
Etiology and Pathogenesis
Clinical Manifestations
Laboratory Examination
Radiologic Examination
Differential Diagnosis
Treatment
Course of the Disease and Prognosis
References
Chapter 31. Acute Rheumatic Fever and Post-streptocococcal Reactive Arthritis
Acute Rheumatic Fever
Post-Streptococcal Reactive Arthritis
Acknowledgment
References
Chapter 32. Musculoskeletal Manifestations of Systemic Disease
Nutritional Abnormalities
Metabolic Diseases
Hematologic Disorders
Disorders of Endocrine and Exocrine Glands
Cystic Fibrosis
Hyperostosis
Pancreatitis with Arthritis
Sphingolipidoses
References
Chapter 33. Immunodeficiencies and the Rheumatic Diseases
Disorders of Innate Immunity Associated with Rheumatic Diseases
Disorders of Adaptive Immunity Associated with Diseases
References
Chapter 34. Periodic Fever Syndromes in Children
Infectious Causes of Periodic Fever Syndromes
Rheumatic Disorders
Hereditary Periodic (Recurrent) Fever Syndromes
References
Chapter 35. Cryopyrin-Associated Periodic Syndromes
Genetics and Etiology
Clinical Manifestations
Treatment
References
Chapter 36. Noninflammatory Musculoskeletal Pain Conditions
Pain Associated with Hypermobility
Pain Syndromes Related to Overuse
Osteochondroses
Trauma-Induced Conditions
Pain Syndromes Affecting the Back, Chest, or Neck
Miscellaneous Conditions
References
Chapter 37. Pain and the Pain Amplification Syndromes
Anatomy, Physiology, and Measurement of Pain
Nociceptive Mechanisms
Modulating (Sensitizing and Inhibiting) Mechanisms
The Child in Pain
Evaluation and Management of Musculoskeletal Pain
Pain Management
Historical Review
Definition and Classification
Epidemiology
Etiology and Pathogenesis
Genetic Background
Clinical Manifestations
Pathology
Differential Diagnosis
General Assessment of Pain
Laboratory Examination
Radiographic Examination
Treatment
Course and Prognosis
Conclusion
References
Primary and Acquired Disorders of Bone and Connective Tissue
Chapter 38. Skeletal Maturation and Bone Mineralization in the Pediatric Rheumatic Diseases
Normal Skeletal Maturation
Diagnostic Methods
Bone Mineralization in the Rheumatic Diseases
Primary and Secondary Bone Mineralization Disorders
Prevention
Treatment
References
Chapter 39. Skeletal Malignancies and Related Disorders
Primary Tumors of Bone, Cartilage, Fibrous or Soft Tissue, or Miscellaneous Origin
Malignant Tumors
Metastatic Bone Tumors
Malignant Infiltration of Bone Marrow: Leukemia
Secondary Effects of Malignancy
Acknowledgment
References
Chapter 40. Primary Disorders of Bone and Connective Tissues
Establishing a Diagnosis
Molecular Mechanisms of Disease

Textbook of pediatric rheumatology /

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