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00000pam a22000004a 4500 |
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4617169 |
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20031021124200.0 |
| 008 |
010524s2001 enka b 001 0 eng |
| 010 |
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|a 2001036071
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|a 019963811X (hbk. : alk. paper)
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|a 0199638101 (pbk. : alk. paper)
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|a 2001036071
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|a DLC
|c DLC
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|d OCoLC
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|a pcc
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| 050 |
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|a RA652
|b .M647 2001
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| 082 |
0 |
0 |
|a 614.4
|2 21
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| 245 |
0 |
0 |
|a Molecular epidemiology :
|b a practical approach /
|c edited by Mary Carrington and A.R. Hoelzel.
|
| 260 |
|
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|a New York :
|b Oxford University Press,
|c 2001.
|
| 300 |
|
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|a xix, 243 p. :
|b ill. ;
|c 26 cm.
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
|0 http://id.loc.gov/vocabulary/contentTypes/txt
|
| 337 |
|
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|a unmediated
|b n
|2 rdamedia
|0 http://id.loc.gov/vocabulary/mediaTypes/n
|
| 338 |
|
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|a volume
|b nc
|2 rdacarrier
|0 http://id.loc.gov/vocabulary/carriers/nc
|
| 440 |
|
0 |
|a Practical approach series ;
|v 251
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 505 |
0 |
0 |
|t Introduction to molecular epidemiology /
|r Charles S. Rabkin and Nathaniel Rothman --
|g 1.
|t Epidemiological methods for studies of genetic factors that influence infectious diseases /
|r Eric A. Engels and Thomas R. O'Brien --
|g 1.
|t General considerations --
|g 2.
|t Types of epidemiological studies --
|g 3.
|t Cohort study --
|g 4.
|t Case-control studies --
|g 5.
|t Cross-sectional studies --
|g 6.
|t Interpretation of epidemiological associations --
|g 7.
|t Confounding --
|g 8.
|t Bradford Hill's criteria for causality --
|g 9.
|t Statistical considerations --
|g 10.
|t Further statistical considerations --
|g 11.
|t Interaction --
|g 12.
|t Identifying candidate genes for epidemiological studies --
|g 13.
|t The future of genetic epidemiology --
|g 2.
|t Molecular differentiation of bacterial strains /
|r Eric W. Brown --
|g 1.
|t Introduction --
|g 2.
|t PCR-based fingerprinting of the bacterial chromosome --
|g 3.
|t RFLP analysis of the bacterial chromosome --
|g 4.
|t PFGE analysis of the bacterial chromosome --
|g 5.
|t DNA sequence analysis of the bacterial ompA gene --
|g 6.
|t Conclusion --
|g 3.
|t Detection and quantification of heterogeneous viral targets: HIV as a model /
|r Shirley Kwok --
|g 1.
|t Introduction --
|g 2.
|t Impact of sequence heterogeneity on PCR --
|g 3.
|t Primer and probe design for HIV --
|g 4.
|t Assay sensitivity and specificity --
|g 5.
|t Preventing false positives from PCR carryover --
|g 6.
|t Amplification target: DNA vs. RNA --
|g 7.
|t Qualitative vs. quantitative assays --
|g 8.
|t Importance of internal controls and quantitation standards --
|g 9.
|t Evaluation of assay performance --
|g 10.
|t Qualitative HIV DNA assay --
|g 11.
|t Quantitative HIV RNA assay --
|g 12.
|t Quantitative DNA asay --
|g 13.
|t Real time detection formats --
|g 4.
|t Mutation detection by single-stranded conformation polymorphism and denaturing high performance liquid chromatography /
|r Michael Dean, Bernard Gerrard and Rando Allikmets --
|g 1.
|t Introduction --
|g 2.
|t Single-stranded conformation polymorphism (SSCP) and heteroduplex analysis (HA) --
|g 3.
|t Denaturing high performance liquid chromatography (DHPLC) --
|g 5.
|t DNA pooling methods for association mapping of complex disease loci /
|r Lisa F. Barcellos, Soren Germer and William Klitz --
|g 1.
|t Introduction --
|g 2.
|t Quantification of DNA samples for pooled amplification --
|g 3.
|t Genetic analysis of microsatellite markers using pooled DNA samples --
|g 4.
|t Analysis of pooled microsatellite data --
|g 5.
|t SNP allele frequency determination using kinetic PCR --
|g 6.
|t Experimental design considerations --
|g 7.
|t DNA pooling in the era of the human genome sequence --
|g 6.
|t Single-sperm typing: a rapid alternative to family-based linkage analysis /
|r Michael Cullen and Mary Carrington --
|g 1.
|t Introduction --
|g 2.
|t Isolation of single sperm --
|g 3.
|t Whole genome amplification of haploid DNA --
|g 4.
|t PCR amplification using PEP reaction products as a source of DNA --
|g 5.
|t Discriminating alleles by gel electrophoresis --
|g 6.
|t Interpretation of sperm typing data --
|g 7.
|t PCR-based methods of HLA typing /
|r Henry A. Erlich and Elizabeth A. Trachtenberg --
|g 1.
|t Introduction --
|g 2.
|t The HLA loci --
|g 3.
|t HLA allelic sequence diversity --
|g 4.
|t Nomenclature --
|g 5.
|t HLA typing: a brief history --
|g 6.
|t HLA typing requirements --
|g 7.
|t The problem of new alleles and of ambiguity --
|g 8.
|t Evolutionary analysis of molecular sequence data /
|r Austin L. Hughes, Jack da Silva and Federica Verra --
|g 1.
|t Introduction --
|g 2.
|t Comparing sequences --
|g 3.
|t Reconstructing phylogenies --
|g 4.
|t Applications.
|
| 650 |
|
0 |
|a Molecular epidemiology
|v Laboratory manuals.
|
| 650 |
|
7 |
|a Molecular epidemiology.
|2 fast
|0 http://id.worldcat.org/fast/fst01024791
|
| 655 |
|
7 |
|a Laboratory manuals.
|2 fast
|0 http://id.worldcat.org/fast/fst01920776
|
| 700 |
1 |
|
|a Carrington, Mary.
|0 http://id.loc.gov/authorities/names/nb2001055282
|1 http://viaf.org/viaf/9350711
|
| 700 |
1 |
|
|a Hoelzel, A. Rus.
|0 http://id.loc.gov/authorities/names/n89143314
|1 http://viaf.org/viaf/84663
|
| 901 |
|
|
|a ToCBNA
|
| 903 |
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|a HeVa
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|a (OCoLC)47054741
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|t Library of Congress classification
|a RA652 .M647 2001
|l JCL
|c JCL-Sci
|i 4602867
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| 927 |
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|t Library of Congress classification
|a RA652 .M647 2001
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