Identifying geographic regions for potential future epidemiology research on disinfection byproducts /
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| Author / Creator: | Raucher, Robert S. |
|---|---|
| Imprint: | Denver, CO : AWWA Research Foundation and American Water Works Association, c2001. |
| Description: | xxiv, 329 p. : ill., maps ; 28 cm. |
| Language: | English |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4641616 |
Table of Contents:
- List of Tables
- List of Figures
- Foreword
- Preface
- Acknowledgments
- Executive Summary
- Chapter 1. Introduction
- Background
- Research Objective
- Approach
- Report Outline
- Chapter 2. Technical Approach
- Introduction
- Selecting Health Endpoints and Epidemiological Study Designs on Which to Focus
- Data Search and Screening Methodology
- Assessing the Availability and Reliability of Health Endpoint Data
- Assessing the Availability and Reliability of Exposure Data
- Overlaying Locations With Both Health and Exposure Data
- Analyzing CWS Exposure Profile Determinants in Greater Detail
- Chapter 3. Data Needs for Epidemiological Research of Disinfection Byproducts
- Introduction
- Existing Health Risk Evidence
- Carcinogenic Endpoints
- Selected Carcinogenic Endpoints
- Developmental and Reproductive Endpoints
- Key Health Endpoints and Their Implications for Epidemiological Study Design
- Cancer Epidemiology
- Reproductive Epidemiology
- Other General Study Design Issues
- Conclusions
- Chapter 4. Availability of Health Data
- Introduction
- Cancer Information Base
- Methods
- Findings
- Adverse Birth Outcomes Information Base
- Methods
- Findings
- Conclusions
- Chapter 5. Matching Community Water Systems with Desired Exposure Profiles
- Introduction
- Caveats and Limitations
- Exposure Profiles of Interest to Future Disinfection Byproducts Epidemiological Research
- Need to Investigate Brominated Disinfection Byproducts and Halacetic Acids in General
- Defining Exposure Profiles of Concern
- Assessment of Available Exposure Data
- Available Data Used in Analyses
- Exposure Characterization Methodology and Results
- Total Organic Carbon, Bromide, and Bromide: Dissolved Organic Carbon Levels
- Average Annual and Maximum Total Trihalomethane and Haloacetic Acid 5 Levels
- Average and Maximum Total Trihalomethane/Haloacetic Acid 5 Combination Maps
- Trihalomethane and Haloacetic Acids Overlap With High Bromide and Bromide: DOC Occurrence
- Intrasystem Trihalomethane and Haloacetic Acids Annual Variability and Overlap With High Bromide Sites
- Information Collection Rule Data Sites, Data Fields, Availability Schedule, and Overlap With Promising Water:\Stats Sites
- Conclusions
- Chapter 6. Promising Study Locations for Cancer Research
- Methods
- Results: Cancer Sites with Total Trihalomethane Data
- Locations With Existing Bromide Data
- Average Total Trihalomethane Concentration
- Locations Including Those Without Bromide Data (but listed as Information Collection Rule Database Sites)
- Other Possible Study Locations
- Results: Cancer Study Sites With Haloacetic Acids Data
- Locations With Bromide Data
- Locations Without Bromide Data (but on Information Collection Rule Database)
- Other Possible Study Locations
- Chapter 7. Promising Study Locations for Adverse Developmental and Reproductive Outcomes
- Introduction
- Birth Defects and Disinfection Byproducts
- Methods
- Results
- Locations Recommended for Study: Total Trihalomethanes and Birth Defects
- Locations Recommended for Study: Haloacetic Acids and Birth Defects
- Adverse Reproductive Outcomes
- Methods
- Results
- Locations Recommended for Study: Total Trihalomethanes and Adverse Reproductive Outcomes
- Locations Recommended for Study: Haloacetic Acids
- Chapter 8. Additional Issues for Consideration
- Intrasystem Variations in Disinfection Byproduct Exposures: Spatial Considerations
- Subsystems Within Community Water Systems
- Disinfection Byproduct Formation and Stability in Distribution Systems
- Intrasystem Variations in Disinfection Byproduct Exposures: Temporal Considerations
- Changes in Disinfection Byproduct Levels Over a Time Frame of Multiple Years
- Seasonal Variation in Disinfection Byproducts
- Other Issues in Disinfection Byproduct Formation and Associated Exposure Assessments
- Modeling Disinfection Byproducts
- Limitations of Using Water:\Stats, Information Collection Rules, and Other Disinfection Byproduct Data Sources for Exposure Assessment
- Other Critical Factors
- Conclusions
- Chapter 9. Suggested Future Research
- Appendix A. Summaries of DBP Epidemiological Studies
- Appendix B. Questionnaire for the Center for Disease Control's Cancer Registry Program Participants
- Appendix C. Water Quality Data for Specific Utilities
- Appendix D. Utilities Meeting Cancer or Birth Defects Epidemiological Study Requirements Reporting High or Low Annual Average, or High Intrasystem, Total Trihalomethane or Haloacetic Acid 5 Levels
- Appendix E. Study Site Characteristics and Ability to Support Epidemiological Studies of Adverse Reproductive Outcomes
- Appendix F. Notes and Caveats on Specific Systems
- References and Supplemental Readings
- Abbbreviations
