The Genetic basis of human cancer /

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Bibliographic Details
Edition:2nd ed.
Imprint:New York : McGraw-Hill, Medical Pub. Division, c2002.
Description:xv, 821 p. : ill. ; 29 cm.
Language:English
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4642945
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Other authors / contributors:Vogelstein, Bert.
Kinzler, Kenneth W.
ISBN:0071370501
Notes:Includes bibliographical references and index.
Table of Contents:
  • Part 1. Basic Concepts in Cancer Genetics
  • 1. Introduction
  • 2. The Nature and Mechanisms of Human Cancer Mutation
  • 3. Genomic Imprinting and Cancer
  • 4. Genes Altered by Chromosomal Translocations in Leukemia and Lymphomas
  • 5. Chromosome Alterations in Human Solid Tumors
  • 6. Gene Amplification in Human Cancers: Biological and Clinical Significance
  • 7. Tumor Genome Instability
  • 8. Gene Expression Profiling in Cancer
  • Part 2. Controls on Cell Cycle
  • 9. Cell Cycle Control: An Overview
  • 10. Apoptosis and Cancer
  • 11. Oncogenes
  • 12. Tumor-Suppressor Genes
  • Part 3. Familial Cancer Syndromes
  • Section I. Overview
  • 13. Familial Cancer Syndromes: Role of Caretakers and Gatekeepers
  • Section II. Defects in Caretakers
  • 14. Nucleotide Excision Repair Syndromes: Xeroderma Pigmentosum, Cockayne Syndrome, and Trichothiodystrophy
  • 15. Ataxia-Telangiectasia
  • 16. Bloom Syndrome
  • 17. Fanconi Anemia
  • 18. Hereditary Nonpolyposis Colorectal Cancer (HNPCC)
  • 19. Werner Syndrome
  • 20. Peutz-Jeghers Syndrome
  • 21. Juvenile Polyposis Syndrome
  • Section III. Defects in Gatekeepers
  • 22. Retinoblastoma
  • 23. Li-Fraumeni Syndrome
  • 24. Wilms Tumor
  • 25. Neurofibromatosis 1
  • 26. Neurofibromatosis 2
  • 27. Renal Carcinoma
  • 28. Multiple Endocrine Neoplasia Type 1
  • 29. Multiple Endocrine Neoplasia Type 2
  • 30. Malignant Melanoma
  • 31. Cowden Syndrome
  • 32. Skin Cancer (Including Nevoid Basal Cell Carcinoma Syndrome)
  • 33. Breast Cancer
  • 34. Colorectal Tumors
  • 35. Pilomatricoma and Pilomatrix Carcinoma
  • 36. Hereditary Paragangliomas of the Head and Neck
  • 37. Cylindromatosis
  • 38. Familial Cardiac Myxomas and Carney Complex
  • Section IV. Managing Familial Cancer Syndromes
  • 39. Genetic Testing for Familial Cancer
  • Part 4. Cancer by Site
  • 40. Pancreatic Cancer
  • 41. Ovarian Cancer
  • 42. Endometrial Cancer
  • 43. Cervical Cancer
  • 44. Bladder Cancer
  • 45. Stomach Cancer
  • 46. Prostate Cancer
  • 47. Brain Tumors
  • 48. Lung Cancer
  • 49. Hepatocellular Carcinoma
  • 50. Clinical and Biological Aspects of Neuroblastoma
  • 51. Cancers of the Oral Cavity and Pharynx
  • 52. Genetic Abnormalities in Lymphoid Mailgnancies