The Genetic basis of human cancer /
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Edition: | 2nd ed. |
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Imprint: | New York : McGraw-Hill, Medical Pub. Division, c2002. |
Description: | xv, 821 p. : ill. ; 29 cm. |
Language: | English |
Subject: | |
Format: | Print Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4642945 |
Table of Contents:
- Part 1. Basic Concepts in Cancer Genetics
- 1. Introduction
- 2. The Nature and Mechanisms of Human Cancer Mutation
- 3. Genomic Imprinting and Cancer
- 4. Genes Altered by Chromosomal Translocations in Leukemia and Lymphomas
- 5. Chromosome Alterations in Human Solid Tumors
- 6. Gene Amplification in Human Cancers: Biological and Clinical Significance
- 7. Tumor Genome Instability
- 8. Gene Expression Profiling in Cancer
- Part 2. Controls on Cell Cycle
- 9. Cell Cycle Control: An Overview
- 10. Apoptosis and Cancer
- 11. Oncogenes
- 12. Tumor-Suppressor Genes
- Part 3. Familial Cancer Syndromes
- Section I. Overview
- 13. Familial Cancer Syndromes: Role of Caretakers and Gatekeepers
- Section II. Defects in Caretakers
- 14. Nucleotide Excision Repair Syndromes: Xeroderma Pigmentosum, Cockayne Syndrome, and Trichothiodystrophy
- 15. Ataxia-Telangiectasia
- 16. Bloom Syndrome
- 17. Fanconi Anemia
- 18. Hereditary Nonpolyposis Colorectal Cancer (HNPCC)
- 19. Werner Syndrome
- 20. Peutz-Jeghers Syndrome
- 21. Juvenile Polyposis Syndrome
- Section III. Defects in Gatekeepers
- 22. Retinoblastoma
- 23. Li-Fraumeni Syndrome
- 24. Wilms Tumor
- 25. Neurofibromatosis 1
- 26. Neurofibromatosis 2
- 27. Renal Carcinoma
- 28. Multiple Endocrine Neoplasia Type 1
- 29. Multiple Endocrine Neoplasia Type 2
- 30. Malignant Melanoma
- 31. Cowden Syndrome
- 32. Skin Cancer (Including Nevoid Basal Cell Carcinoma Syndrome)
- 33. Breast Cancer
- 34. Colorectal Tumors
- 35. Pilomatricoma and Pilomatrix Carcinoma
- 36. Hereditary Paragangliomas of the Head and Neck
- 37. Cylindromatosis
- 38. Familial Cardiac Myxomas and Carney Complex
- Section IV. Managing Familial Cancer Syndromes
- 39. Genetic Testing for Familial Cancer
- Part 4. Cancer by Site
- 40. Pancreatic Cancer
- 41. Ovarian Cancer
- 42. Endometrial Cancer
- 43. Cervical Cancer
- 44. Bladder Cancer
- 45. Stomach Cancer
- 46. Prostate Cancer
- 47. Brain Tumors
- 48. Lung Cancer
- 49. Hepatocellular Carcinoma
- 50. Clinical and Biological Aspects of Neuroblastoma
- 51. Cancers of the Oral Cavity and Pharynx
- 52. Genetic Abnormalities in Lymphoid Mailgnancies