Handbook of optical biomedical diagnostics /

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Bibliographic Details
Imprint:Bellingham, Wash. : SPIE Press, c2002.
Description:xv, 1093 p. : ill. ; 27 cm.
Language:English
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4674606
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Other authors / contributors:Tuchin, V. V. (Valeriì† Viktorovich)
ISBN:0819442380
Notes:Includes bibliographical references and index.
Table of Contents:
  • Preface
  • Introduction to Optical Biomedical Diagnostics
  • Part I.. Light-Tissue Interaction--Diagnostical Aspects
  • Introduction
  • Chapter 1.. Introduction to Light Scattering by Biological Objects
  • 1.1. Introduction
  • 1.2. Extinction and Scattering of Light in Disperse Systems: Basic Theoretical Approaches
  • 1.3. Theoretical Methods for Single-Particle Light-Scattering Calculations
  • 1.4. Extinction and Scattering by Aggregated and Compounded Structures
  • 1.5. Spectroturbidimetry of Disperse Systems with Random and Oriented Particles
  • 1.6. Tissue Structure and Relevant Optical Models
  • 1.7. Light Scattering by Densely Packed Correlated Particles
  • 1.8. Application of Radiative Transfer Theory to the Tissue Optics
  • 1.9. Nephelometry and Polarization Methods for the Diagnostics of Bio-objects
  • 1.10. Controlling of Optical Properties of Tissues
  • 1.11. Summary
  • Acknowledgments
  • Abbreviations
  • References
  • Chapter 2.. Optics of Blood
  • 2.1. Introduction
  • 2.2. Physical Properties of Blood Cells
  • 2.3. Optical Properties of Oxyhemoglobin and Deoxyhemoglobin
  • 2.4. Absorption and Scattering of Light by a Single Erythrocyte
  • 2.5. Optical Properties of Blood
  • 2.6. Summary of the Optical Properties of Diluted and Whole Human Blood
  • 2.7. Practical Relevance of Blood Optics
  • References
  • Chapter 3.. Propagation of Pulses and Photon Density Waves in Turbid Media
  • 3.1. Introduction
  • 3.2. Time-Dependent Transport Theory
  • 3.3. Techniques for Solving the Time-Dependent Transport Equation
  • 3.4. Monte Carlo Method
  • 3.5. Diffusion Approximation
  • 3.6. Beyond Diffusion Approximation
  • 3.7. Role of the Single-Scattering Delay Time
  • 3.8. Concluding Remarks
  • References
  • Chapter 4.. Coherence Phenomena and Statistical Properties of Multiply Scattered Light
  • 4.1. Introduction
  • 4.2. Weak Localization of Light in Disordered and Weakly Ordered Media
  • 4.3. Correlation Properties of Multiply Scattered Coherent Light: Basic Principles and Methods
  • 4.4. Evaluation of Pathlength Density: Basic Approaches
  • 4.5. Manifestations of Similarity in Multiple Scattering of Coherent Light by Disordered Media
  • 4.6. Conclusion
  • Acknowledgments
  • References
  • Chapter 5.. Tissue Phantoms
  • 5.1. Introduction
  • 5.2. General Approach to Phantom Development
  • 5.3. Scattering Media for Phantom Preparation
  • 5.4. Light-Absorbing Media for Phantom Preparation
  • Acknowledgment
  • References
  • Part II.. Pulse and Frequency-Domain Techniques for Tissue Spectroscopy and Imaging
  • Introduction
  • Chapter 6.. Time-resolved Imaging in Diffusive Media
  • 6.1. Introduction
  • 6.2. General Concepts in Time-resolved Imaging Through Highly Diffusive Media
  • 6.3. Experimental Tools for Time-resolved Imaging
  • 6.4. Technical Designs for Time-resolved Imaging
  • 6.5. Toward Clinical Applications
  • 6.6. Conclusions
  • References
  • Chapter 7.. Frequency-Domain Techniques for Tissue Spectroscopy and Imaging
  • 7.1. Introduction
  • 7.2. Instrumentation, Modulation Methods, and Signal Detection
  • 7.3. Modeling Light Propagation in Scattering Media
  • 7.4. Tissue Spectroscopy and Oximetry
  • 7.5. Optical Imaging of Tissues
  • 7.6. Future Directions
  • Acknowledgments
  • References
  • Chapter 8.. Monitoring of Brain Activity with Near-Infrared Spectroscopy
  • 8.1. Introduction
  • 8.2. Continuous Light Functional Near-Infrared Imager
  • 8.3. Monitoring Human Brain Activity with a CW Functional Optical Imager
  • 8.4. Future Prospects
  • References
  • Chapter 9.. Signal Quantification and Localization in Tissue Near-Infrared Spectroscopy
  • 9.1. Introduction
  • 9.2. Oximetry
  • 9.3. Tissue Near-Infrared Spectroscopy
  • 9.4. Spectroscopy in a Highly Scattering Medium
  • 9.5. Absolute Measurements
  • 9.6. Quantified Trend Measurements
  • 9.7. Use of Quantified Trend Measurements to Infer Absolute Blood Flow, Blood Volume, Hemoglobin Saturation, and Tissue Oxygen Consumption
  • 9.8. Effects of Tissue Geometry and Heterogeneity
  • 9.9. Chapter Summary
  • References
  • Chapter 10.. Time-Resolved Detection of Optoacoustic Profiles for Measurement of Optical Energy Distribution in Tissues
  • 10.1. Methods to Study Light Distribution in Tissue
  • 10.2. Two Modes of Optoacoustic Detection
  • 10.3. Historical Remarks on Time-Resolved Optoacoustics
  • 10.4. Time-Resolved Optoacoustics in a Microheterogeneous Medium
  • 10.5. Laser-Induced Ultrasonic Transients in Biological Tissue
  • 10.6. Technical Requirements for Time-Resolved Stress Detection
  • 10.7. Measurement of Optical Properties with the Optoacoustic Technique
  • 10.8. Summary and Applications
  • References
  • Part III.. Scattering, Fluorescence, and Infrared Fourier Transform Spectroscopy of Tissues
  • Introduction
  • Chapter 11.. Light Backscattering Diagnostics of Red Blood Cell Aggregation in Whole Blood Samples
  • 11.1. Introduction. Microrheological Structure of Blood: Biophysical and Clinical Aspects
  • 11.2. Importance of Quantitative Measurement of RBC Aggregation and Deformability Parameters
  • 11.3. Arrangement of a Couette Chamber-based Laser Backscattering Aggregometer
  • 11.4. Kinetics of the Aggregation and Disaggregation Process
  • 11.5. Parameters Influencing the Aggregation and Disaggregation Measurements
  • 11.6. Comparison of Aggregation and Disaggregation Measurements with Sedimentation Measurements
  • 11.7. Determination of Different Diseases by Aggregation and Disaggregation Measurements of Blood Samples
  • References
  • Chapter 12.. Light Scattering Spectroscopy of Epithelial Tissues: Principles and Applications
  • 12.1. Introduction
  • 12.2. Microscopic Architecture of Mucosal Tissues
  • 12.3. Principles of Light Scattering
  • 12.4. Light Scattering by Cells and Subcellular Structures
  • 12.5. Light Transport in Superficial Tissues
  • 12.6. Detection of Cancer with Light Scattering Spectroscopy
  • Acknowledgments
  • References
  • Chapter 13.. Reflectance and Fluorescence Spectroscopy of Human Skin In Vivo
  • 13.1. Introduction
  • 13.2. Human Skin Back Reflectance and Autofluorescence Spectra Formation
  • 13.3. Simple Optical Models of Human Skin
  • 13.4. Combined Reflectance and Fluorescence Spectroscopy Method for In Vivo Skin Examination
  • 13.5. Color Perception of Human Skin Back Reflectance and Fluorescence Emission
  • 13.6. Polarization Imaging
  • 13.7. Sunscreen Evaluation using Reflectance and Fluorescence Spectroscopy
  • 13.8. Control of Skin Optical Properties
  • 13.9. Conclusions
  • References
  • Chapter 14.. Infrared and Raman Spectroscopy of Human Skin In Vivo
  • 14.1. Introduction: Basic Principles of IR and Raman Spectroscopy
  • 14.2. Fourier Transform Infrared Spectroscopy of Human Skin Stratum Corneum In Vivo
  • 14.3. Confocal Raman Microspectroscopy of Human Skin In Vivo
  • 14.4. Conclusions and Outlook
  • Acknowledgment
  • References
  • Chapter 15.. Fluorescence Technologies in Biomedical Diagnostics
  • 15.1. Introduction
  • 15.2. Intrinsic and Extrinsic Fluorescence
  • 15.3. Spectroscopic, Microscopic, and Imaging Techniques
  • 15.4. Time-Resolved Fluorescence Spectroscopy and Imaging
  • 15.5. Total Internal Reflection Fluorescence Spectroscopy and Microscopy (TIRFS/TIRFM)
  • 15.6. Energy Transfer Spectroscopy
  • 15.7. Laser Scanning and Multiphoton Microscopy
  • References
  • Part IV.. Coherent-Domain Methods for Biological Flows and Tissue Ultrastructure Monitoring
  • Introduction
  • Chapter 16.. Speckle and Doppler Methods of Blood and Lymph Flow Monitoring
  • 16.1. Introduction
  • 16.2. Classification of the Blood and Lymph Flow in Capillaries: Hydrodynamic and Optics Aspects
  • 16.3. Physiology of Lymph Microcirculation
  • 16.4. Theory of Speckle Interferometry of Bioflows
  • 16.5. Experimental Investigations of Bioflows
  • 16.6. Doppler and Speckle Techniques
  • 16.7. Conclusions
  • Acknowledgments
  • References
  • Chapter 17.. Real-Time Imaging of Microstructure and Blood Flows Using Optical Coherence Tomography
  • 17.1. Introduction
  • 17.2. Optical Coherence Tomography
  • 17.3. Real-Time Optical Coherence Tomography
  • 17.4. Applications of Real-Time OCT in Ophthalmology and Dermatology
  • 17.5. Endoscopic Optical Coherence Tomography
  • 17.6. Color Doppler Optical Coherence Tomography
  • 17.7. Conclusions and Acknowledgments
  • References
  • Chapter 18.. Speckle Technologies for Monitoring and Imaging of Tissues and Tissuelike Phantoms
  • 18.1. Introduction
  • 18.2. Diffusing-Wave Spectroscopy (DWS) as a Tool for Tissue Structure and Cell Flow Monitoring
  • 18.3. Flow Measurement by Laser Speckle Contrast Analysis (LASCA)
  • 18.4. Modification of Speckle Contrast Analysis to Improve Depth Resolution
  • 18.5. Spatial Speckle Correlometry Applied to Tissue Structure Diagnostics and Imaging
  • 18.6. Imaging Using Contrast Measurements of Partially Coherent Speckles
  • 18.7. Summary
  • Acknowledgment
  • References
  • Chapter 19.. Optical Assessment of Tissue Mechanics
  • Additional Nomenclature of Definitions
  • 19.1. Introduction
  • 19.2. Tissue Mechanics and Medicine
  • 19.3. Constitutive Relations in Biological Tissues
  • 19.4. Laser Speckle Patterns Arising from Biological Tissues
  • 19.5. Elastography Measurements by Tracking Translating Speckle: The Transform Method
  • 19.6. Alternative Processing Algorithms for Calculating Speckle Shift
  • 19.7. Acoustically Modulated Speckle Imaging
  • 19.8. Elastography of Tissues with Optical Coherence Tomography
  • 19.9. Conclusions
  • References
  • Index