Microbial DNA and host immunity /
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Imprint: | Totowa, N.J. : Humana Press, c2002. |
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Description: | xvii, 408 p. : ill. ; 23 cm. |
Language: | English |
Subject: | |
Format: | E-Resource Print Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/4781353 |
Table of Contents:
- Preface
- Contributors
- Part I. Introduction
- 1. Immunostimulatory DNA: An Overview
- 2. Historical Perspectives
- Part II. Receptors and Signaling
- 3. Signal Transduction Pathways Activated By CpG-DNA
- 4. A Novel Toll-Like Receptor that Recognizes Bacterial DNA
- 5. Activation of Innate Immunity by Microbial Nucleic Acids
- 6. Phosphorothioate Backbone Modification Changes the Pattern of Responses to CpG
- Part III. Cell Activation
- 7. Activation of NK Cell By Immunostimulatory Oligo-DNA in Mouse and Human
- 8. Regulation of Antigen Presenting Cell Function by CpG DNA
- 9. Activation of B Cells by CpG Motifs in Bacterial DNA
- 10. IFN-Dependent Pathways for Stimulation of Memory CD8[superscript +] Cells
- 11. Cross-Priming of CD8[superscript +] T Cells by Immunostimulatory Sequence DNA
- Part IV. Vaccination Strategies
- 12. The Th1 Adjuvant Effect of Immunostimulatory (ISS) DNA Sequences
- 13. Immunostimulatory DNA Prepriming for the Induction of Th1 and Prevention of Th2 Biased Immune Responses
- 14. Protein-Immunostimulatory DNA-Conjugate: A Novel Immunogen
- 15. Immunostimulatory DNA Sequence-Based Mucosal Vaccines
- 16. Enhancement of the Immunoadjuvant Activity of Immunostimulatory DNA Sequence by Liposomal Delivery
- 17. Immunostimulatory Sequences in Plasmid Vectors
- Part V. Applications--Infectious Disease
- 18. Comparison of CpG DNA with Other Adjuvants for Vaccination Against Hepatitis B
- 19. Immunostimulatory DNA-Based Immunization: Hope for an HIV Vaccine?
- 20. Immunoprotective Activity of CpG Oligonucleotides
- 21. Protective Immunity of Immunostimulatory Sequences Against Mycobacterial Infection
- Part VI. Applications--Allergy
- 22. DNA-Based Immunotherapeutics For Allergic Disease
- 23. Immunostimulatory DNA for Allergic Asthma
- 24. CpG Oligodeoxynucleotides in Asthma
- 25. Modulation of Allergic Conjunctivitis by Immunostimulatory DNA Sequence Oligonucleotides
- Part VII. Applications--Cancer
- 26. CpG Oligodeoxynucleotides and Monoclonal Antibody Therapy of Lymphoma
- Part VIII. Inflammation and Autoimmunity
- 27. The Antigenicity of Bacterial DNA
- 28. Inflammatogenic Properties of Immunostimulatory DNA Sequences
- 29. The Role of Immunostimulatory DNA Sequences in Arthritis
- 30. Effects of Immunostimulatory DNA Oligonucleotides on Experimental Colitis
- Part IX. Saffty Considerations
- 31. CpG ODN--Safety Considerations
- Index