Tumor suppressor genes /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, c2003.
Description:xix, 657 p. : ill. ; 26 cm.
Language:English
Series:Methods in molecular biology ; v. 222-223
Methods in molecular biology (Clifton, N.J.) ; v. 222-223.
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/4868635
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Other authors / contributors:El-Deiry, Wafik S.
ISBN:0896039862 (v. 1 : alk. paper)
0896039870 (v. 2 : alk. paper)
1592593283 (e-ISBN)
Notes:Includes bibliographical references and index.
Table of Contents:
  • Preface
  • Contents of Companion Volume
  • Contributors
  • Part I. Known Tumor Suppressor Genes and Pathways
  • 1. Growth Control by the Retinoblastoma Gene Family
  • 2. The APC Tumor Suppressor Pathway
  • 3. Hereditary Breast and Ovarian Cancer Genes
  • 4. Hereditary Colon Cancer Genes
  • 5. Patched, Hedgehog, and Skin Cancer
  • 6. Tumor Suppressor Genes in Lung Cancer
  • 7. TP53, hChk2, and the Li-Fraumeni Syndrome
  • 8. Genetic Alterations in Esophageal Cancer
  • 9. PTEN and Cancer
  • 10. VHL and Kidney Cancer
  • 11. p16[superscript INK4A] and Familial Melanoma
  • 12. The INK4a/ARF Locus and Human Cancer
  • 13. Progression Model of Prostate Cancer
  • 14. Neurofibromatosis Type 1
  • 15. Wilms' Tumor as a Model for Cancer Biology
  • 16. Inadequate "Caretaker" Gene Function and Human Cancer Development
  • 17. The Regulation of Tumor Suppressor Genes by Oncogenes
  • Part II. Identification of Tumor Suppressor Genes
  • 18. Determination of Cancer Allelotype
  • 19. Epidemiological Approaches to the Identification of Cancer Predisposition Genes
  • 20. Characterization of Translocations in Human Cancer
  • 21. Positional Approaches to Cancer Genetics
  • 22. Hybrid Capture of Putative Tumor Suppressor Genes
  • 23. Approaches to Proteomic Analysis of Human Tumors
  • 24. Representational Difference Analysis of Gene Expression
  • 25. Antisense Libraries to Isolate Tumor Suppressor Genes
  • 26. Genetic Suppressor Elements in the Characterization and Identification of Tumor Suppressor Genes
  • 27. Cross-linking Subtractive Hybridization to Identify Tumor Suppressor Genes
  • 28. Suppression Subtractive Hybridization for Identification and Functional Analysis of Tumor Suppressor Genes
  • 29. SAGE as a Strategy to Isolate Cancer-Related Genes
  • 30. Differential Display Techniques to Identify Tumor Suppressor Gene Pathways
  • 31. Detection of Mismatch Repair Gene Expression in Urologic Malignancies
  • Index