Oncogene-directed therapies /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, c2003.
Description:xiii, 486 p. : ill. (some col.) ; 26 cm.
Language:English
Series:Cancer drug discovery and development
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/5136177
Hidden Bibliographic Details
Other authors / contributors:Rak, Janusz.
ISBN:089603982X (alk. paper)
Notes:Includes bibliographical references and index.

MARC

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300 |a xiii, 486 p. :  |b ill. (some col.) ;  |c 26 cm. 
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440 0 |a Cancer drug discovery and development 
504 |a Includes bibliographical references and index. 
505 0 0 |g Pt. I.  |t Basic Concepts in Oncogene Research --  |g 1.  |t Genetic Basis of Cancer Progression /  |r Susan J. Done and Jeremy A. Squire --  |g 2.  |t The Molecular Basis of Chromosomal Instability in Human Cancer Cells /  |r Daniel P. Cahill --  |g 3.  |t Signal Transduction Networks: Ras as a Paradigm /  |r Frank McCormick --  |g 4.  |t Oncogenic Receptor Tyrosine Kinases /  |r Mark H. Kirschbaum, Mina D. Marmor and Yosef Yarden --  |g 5.  |t Ras-Mediated Deregulation of Gene Expression and Contribution to Oncogenesis /  |r Gretchen A. Murphy and Channing J. Der --  |g 6.  |t The Interplay Between Tumor Suppressor Genes and Oncogenes in Tumorigenesis /  |r Eric C. Holland --  |g 7.  |t Genetic Basis of Altered Responsiveness of Cancer Cells to Their Microenvironment /  |r Amato J. Giaccia --  |g Pt. II.  |t The Functional Impact of Oncogene Expression on Cancer Cells - Therapeutic Implications --  |g 8.  |t Deregulation of Cell Cycle Progression by Oncogenic Transformation /  |r Marcelo L. Rodriguez-Puebla, Adrian M. Senderowicz and Claudio J. Conti --  |g 9.  |t Oncogenes as Regulators of Cell Survival: The Role of Oncogenes and Tumor Suppressor Genes in the Induction of Resistance to Anoikis and Hypoxia /  |r Kirill Rosen and Jorge Filmus --  |g 10.  |t Oncogenes and Tumor Angiogenesis /  |r Janusz Rak and Robert S. Kerbel --  |g 11.  |t Oncogenes as Therapeutic Targets to Prevent Metastasis /  |r Ann F. Chambers and Hemanth J. Varghese --  |g 12.  |t The Impact of Oncogenes on Tumor Maintenance /  |r Senji Shirasawa and Takehiko Sasazuki --  |g 13.  |t Primary and Secondary Events in Oncogene-Driven Tumor Development: Lessons from Transgenic Model Systems /  |r Michaela Herzig and Gerhard Christofori --  |g Pt. III.  |t Oncogenes as Targets for Anticancer Therapy In Vivo --  |g 14.  |t Targeting Oncogenes in Hematopoietic Malignancies /  |r Michael E. O'Dwyer and Brian J. Druker --  |g 15.  |t Clinical Evaluation of Agents Targeting Epidermal Growth Factor Receptor (EGFR) in Cancer /  |r Edward H. Lin and James L. Abbruzzese --  |g 16.  |t Inhibition of the HER-2/neu Oncogene: A Translational Research Model for the Development of Future Targeted Therapies /  |r Gottfried E. Konecny, Jane Arboleda, Dennis J. Slamon and Mark Pegram --  |g 17.  |t Farnesyltransferase Inhibitors as Anticancer Agents /  |r Adrienne D. Cox --  |g 18.  |t Targeting Oncogenic Signaling Pathways in Human Astrocytomas /  |r Gelareh Zadeh and Abhijit Guha --  |g 19.  |t Targeting Oncogenes in Pediatric Malignancies /  |r Giannoula Klement and Robert S. Kerbel --  |g 20.  |t Inhibiting Signal Transduction as an Approach to Radiosensitizing Tumor Cells /  |r Eric J. Bernhard, Anjali K. Gupta, Elizabeth Cohen-Jonathan, Ruth J. Muschel, Stephen M. Hahn and W. Gillies McKenna --  |g 21.  |t Oncogenes as Targets for Cancer Vaccines /  |r Samir N. Khleif and Joseph A. Lucci III --  |g 22.  |t Bcl-2 Antisense Oligonucleotides Therapy for Cancer: Targeting the Mitochondria /  |r Finbarr E. Cotter and Dean A. Fennell. 
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