Antisense therapeutics /
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Edition: | 2nd ed. |
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Imprint: | Totowa, N.J. : Humana Press, c2005. |
Description: | xii, 327 p. : ill. ; 23 cm. |
Language: | English |
Series: | Methods in molecular medicine ; 106 |
Subject: | |
Format: | Print Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/5531622 |
Table of Contents:
- Foreword
- Preface
- Contributors
- Part I. Introduction
- 1. Antisense Therapeutics: A Promise Waiting to be Fulfilled
- 2. Antisense Inhibition: Oligonucleotides, Ribozymes, and siRNAs
- Part II. Cardiovascular
- 3. Local Application of Antisense for Prevention of Restenosis
- 4. Antisense Therapeutics for Hypertension: Targeting the Renin-Angiotensin System
- 5. Antisense Strategies for the Treatment of Heart Failure
- Part III. Cancer
- 6. Clinical Studies of Antisense Oligonucleotides for Cancer Therapy
- 7. Antisense Therapy in Clinical Oncology: Preclinical and Clinical Experiences
- 8. Radionuclide-Peptide Nucleic Acid Diagnosis and Treatment of Pancreatic Cancer
- 9. Suppression of Pancreatic and Colon Cancer Cells by Antisense K-ras RNA Expression Vectors
- 10. Induction of Tumor Cell Apoptosis and Chemosensitization by Antisense Strategies
- 11. Utility of Antioncogene Ribozymes and Antisense Oligonucleotides in Reversing Drug Resistance
- Part IV. Blood-Brain Barrier
- 12. Transport of Antisense Across the Blood-Brain Barrier
- Part V. Dermal
- 13. Transdermal Delivery of Antisense Oligonucletoides
- Part VI. Drugs
- 14. Antisense Strategies for Redirection of Drug Metabolism: Using Paclitaxel as a Model
- Part VII. Gastrointestinal
- 15. Antisense Oligonucleotide Treatment of Inflammatory Bowel Diseases
- Part VIII. Hepatitis
- 16. Optimizing Electroporation Conditions for the Intracellular Delivery of Morpholino Antisense Oligonucleotides Directed Against the Hepatitis C Virus Internal Ribosome Entry Site
- Index