Contemporary drug synthesis /

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Bibliographic Details
Imprint:	Hoboken, N.J. : Wiley-Interscience, c2004.
Description:	xv, 221 p. : ill. ; 25 cm.
Language:	English
Subject:	Pharmaceutical chemistry. Pharmaceutical chemistry.
Format:	Print Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/5537037

Hidden Bibliographic Details
Other authors / contributors:	Li, Jie Jack.
ISBN:	0471214809
Notes:	Includes bibliographical references and index.

Table of Contents:

Preface
Table of Contents
Trade Names and Their Corresponding USANs
Acronyms and Abbreviations
Chapter 1.. Antithrombotics: Ticlopidine (Ticlid) and Clopidogrel (Plavix)
1.1. Introduction
1.2. Syntheses of ticlopidine
1.3. Syntheses of clopidogrel
1.4. References
Chapter 2.. Anti-inflammatory Cyclooxygenase-2 Selective Inhibitors: Celecoxib (Celebrex) and Rofecoxib (Vioxx)
2.1. Introduction
2.2. Synthesis of celecoxib
2.3. Syntheses of rofecoxib
2.4. References
Chapter 3.. H[superscript +]/K[superscript +]-ATPase Inhibitors: Esomeprazole (Nexium)
3.1. Introduction
3.2. Synthesis of esomeprazole
3.2.1. Separation using HPLC
3.2.2. Asymmetric oxidation of the sulfide
3.2.3. Biooxidation
3.3. References
Chapter 4.. Protein-tyrosine Kinase Inhibitors: Imatinib (Gleevec) and Gefitinib (Iressa)
4.1. Introduction to Gleevec
4.2. Synthesis of imatinib mesylate
4.3. Introduction to Iressa
4.4. Synthesis of gefitinib
4.5. References
Chapter 5.. Non-sedating Antihistamines
5.1. Introduction
5.2. Synthesis of loratadine and desloratadine
5.3. Synthesis of fexofenadine
5.4. Synthesis of cetirizine
5.5. References
Chapter 6.. Cosmeceuticals: Isotretinoin (Accutane), Tazarotene (Tazorac), Minoxidil (Rogaine), and Finasteride (Propecia)
6.1. Isotretinoin
6.1.1. Introduction to isotretinoin
6.1.2. Synthesis of isotretinoin
6.2. Tazarotene
6.2.1. Introduction to tazarotene
6.2.2. Synthesis of tazarotene
6.3. Minoxidil
6.3.1. Introduction to minoxidil
6.3.2. Synthesis of minoxidil
6.4. Finasteride
6.4.1. Introduction to finasteride
6.4.2. Synthesis of finasteride
6.5. References
Chapter 7.. Antibacterials: Ciprofloxacin (Cipro) and Linezolid (Zyvox)
7.1. Ciprofloxacin (Cipro)
7.1.1. Introduction to ciprofloxacin
7.1.2. Synthesis of ciprofloxacin
7.2. Linezolid (Zyvox)
7.2.1. Introduction to linezolid
7.2.2. Synthesis of linezolid
7.3. References
Chapter 8.. Atypical Antipsychotics
8.1. Introduction
8.2. Synthesis of risperidone
8.3. Synthesis of olanzapine
8.4. Synthesis of quetiapine fumarate
8.5. Synthesis of ziprasidone
8.6. Synthesis of aripiprazole
8.7. References
Chapter 9.. Atorvastatin Calcium (Lipitor)
9.1. Background
9.2. Synthesis of racemic atorvastatin
9.3. Enantioselective syntheses of atorvastatin calcium
9.4. References
Chapter 10.. Antidepressants
10.1. Background
10.2. Synthesis of fluoxetine hydrochloride
10.3. Synthesis of sertraline hydrochloride
10.4. Synthesis of paroxetine hydrochloride
10.5. References
Chapter 11.. Anti-obesity: Orlistat (Xenical)
11.1. Introduction
11.2. Synthesis of orlistat
11.3. References
Chapter 12.. Triptans for Migraine
12.1. Introduction
12.2. Synthesis of sumatriptan
12.3. Synthesis of zolmitriptan
12.4. Synthesis of naratriptan
12.5. Synthesis of rizatriptan
12.6. Synthesis of almotriptan
12.7. Synthesis of frovatriptan
12.8. Synthesis of eletriptan
12.9. References
Chapter 13.. PDE 5 Inhibitors for Erectile Dysfunction: Sildenafil (Viagra), Vardenafil (Levitra), and Tadalafil (Cialis)
13.1. Introduction
13.2. Discovery and synthesis of sildenafil
13.3. Synthesis of vardenafil
13.4. Synthesis of tadalafil
13.5. References
Chapter 14.. Antiasthmatics
14.1. Introduction
14.2. Synthesis of fluticasone propionate
14.3. Synthesis of salmeterol xinafoate
14.4. Synthesis of montelukast sodium
14.5. References
Index

Contemporary drug synthesis /

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