Signal transduction pathways, chromatin structure, and gene expression mechanisms as therapeutic targets /
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| Imprint: | New York, N.Y. : New York Academy of Sciences, 2004. |
|---|---|
| Description: | xiii, 674 p. : ill. ; 24 cm. |
| Language: | English |
| Series: | Annals of the New York Academy of Sciences ; v. 1030 |
| Subject: | |
| Format: | E-Resource Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/5603514 |
Table of Contents:
- Preface / Marc Diederich
- A beginner's guide to NF-[kappa]B signaling pathways / Sylvie Delhalle, Romain Blasius, Mario Dicato and Marc Diederich
- The vascular endothelial growth factor-induced disruption of gap junctions is relayed by an autocrine communication via ATP release in coronary capillary endothelium / Dominique Thuringer
- Exogenous tissue inhibitor of metalloproteinase-1 promotes endothelial cell survival through activation of the phosphatidylinositol 3-kinase/Akt pathway / Gwenola Boulday, Juliette Fitau, Stephanie Coupel, Jean-Paul Soulillou and Beatrice Charreau
- The cyclooxygenase inhibitor flurbiprofen reduces radiation-induced angiogenic growth factor secretion of squamous cell carcinoma cell lines / Jurgen Brieger, Petra Schroeder, Jan Gosepath and Wolf J. Mann
- Spontaneous generation of reactive oxygen species in the mixture of cyanide and glycerol / Yang-Sook Chun, Eun-Jin Yeo, Hwa-Jin Suh and Jong-Wan Park
- Design and characterization of a new class of inhibitors of ras activation / Sonia Colombo, Francesco Peri, Renata Tisi, Francesco Nicotra and Enzo Martegani
- Endogenous oxidative stress induces distinct redox forms of tumor necrosis factor receptor-1 in melanoma cells / S. Dominici, L. Pieri, A. Paolicchi, V. de Tata, F. Zunino and A. Pompella
- Epidermal growth factor receptor as a novel therapeutic target in anaplastic thyroid carcinomas / C. Ensinger, G. Spizzo, P. Moser, I. Tschoerner, R. Prommegger, M. Gabriel, G. Mikuz and K. W. Schmid
- Analysis of the effects of different alcohols on MCF-7 human breast cancer cells / Nicolas Etique, Dominique Chardard, Amand Chesnel, Stephane Flament and Isabelle Grillier-Vuissoz
- Redox signaling by ionizing radiation in mouse liver / Jeung Hee An, Jiyoung Kim and Jinsil Seong
- Enhancement of tumor response by farnesyltransferase inhibitor in C3H/HeJ hepatocarcinoma / Jiyoung Kim, Jinsil Seong and Sung Hee Kim
- Three-dimensional bioreactor cultures : a useful dynamic model for the study of cellular interactions / Spiro M. Konstantinov, Mina M. Mindova, Panayot T. Gospodinov and Penka I. Genova
- Platelet-activating factor receptor signals in rat osteoblasts during spaceflight / Yasuhiro Kumei, Sadao Morita, Hiroshi Nakamura, Hideo Akiyama, Hisako Katano, Hitoyata Shimokawa and Kei'ichi Ohya
- Osteoblast responsiveness to 1[alpha],25-dihydroxyvitamin D[subscript 3] during spaceflight / Yasuhiro Kumei, Sadao Morita, Hiroshi Nakamura, Hisako Katano, Kei'ichi Ohya, Hitoyata Shimokawa, Clarence F. Sams and Peggy A. Whitson
- Low-grade inflammation with aging has consequences for T-lymphocyte signaling / Anis Larbi, Gilles Dupuis, Nadine Douziech, Abdelouahed Khalil and Tamas Fulop, Jr.
- Role of the hedgehog/patched signaling pathway in oncogenesis : a new polymorphism in the PTCH gene in ovarian fibroma / Sonja Levanat, Vesna Musani, Arijana Komar and S. Oreskovic
- Effects of oxalate on IMCD cells : a line of mouse inner medullary collecting duct cells / Paul D. Maroni, Sweaty Koul, Randall B. Meacham, Paramjit S. Chandhoke and Hari K. Koul
- Supervision of multiple signaling protein kinases by the CK2-Cdc37 couple, a possible novel cancer therapeutic target / Yoshihiko Miyata and Eisuke Nishida
- Hypergravity stimulates osteoblast phenotype expression : a therapeutic hint for disuse bone atrophy / Sadao Morita, Hiroshi Nakamura, Yasuhiro Kumei, Hitoyata Shimokawa, Keiichi Ohya and Kenichi Shinomiya
- CXCR4 activation induces epidermal growth factor receptor transactivation in an ovarian cancer cell line / Carola Porcile, Adriana Bajetto, Simone Barbero, Paolo Pirani and Gennaro Schettini
- Downregulation of angiogenic factors in Ewing tumor xenografts by the combination of human interferon-[alpha] or interferon-[beta] with ifosfamide / Josiane Sanceau and Juana Wietzerbin
- Radiation-induced alteration of pain-related signals in an animal model with bone invasion from cancer / Jinsil Seong, Hee Chul Park, Jiyoung Kim, Un Jung Kim and Bae Whan Lee
- Analysis of the signal transduction pathway leading to human immunodeficiency virus-1-induced interferon regulatory factor-1 upregulation / Marco Sgarbanti, Giulia Marsili, Anna Lisa Remoli, Barbara Ridolfi, Emilia Stellacci, Alessandra Borsetti, Barbara Ensoli and Angela Battistini
- Macrophage hemoglobin scavenger receptor and ferritin accumulation in human atherosclerotic lesions / Wei Li, Li-Hua Xu and Xi-Ming Yuan
- Enhanced expression of natural resistance-associated macrophage protein 1 in atherosclerotic lesion may be associated with oxidized lipid-induced apoptosis / Wei Li, Anna Hellsten, Jerome Dinga Nyhalah and Xi-Ming Yuan
- Regulation of tumor cell motility by ERK mitogen-activated protein kinases / Emmanuel Vial and Jacques Pouyssegur
- Role of constitutively activated and insulin-like growth factor-stimulated ERK 1/2 signaling in human hepatoma cell proliferation and apoptosis : evidence for heterogeneity of tumor cell lines / Catherine Alexia, Malika Lasfer and Andre Groyer
- Cooperative effects between protein kinase A and p44/p42 mitogen-activated protein kinase to promote cAMP-responsive element binding protein activation after [beta] cell stimulation by glucose and its alteration due to glucotoxicity / Safia Costes, Christine Longuet, Christophe Broca, Omar Faruque, El Habib Hani, Dominique Bataille and Stephane Dalle
- p42/p44 mitogen-activated protein kinase signal transduction pathway : a novel target for the treatment of hormone-resistant prostate cancer? / Hari K. Koul, Paul D. Maroni, Randall B. Meacham, David Crawford and Sweaty Koul
- p42/p44 mitogen-activated protein kinase signal transduction pathway regulates interleukin-6 expression in PC3 cells, a line of hormone-refractory prostate cancer cells / Sweaty Koul, Mei Huang, Lakshmi Chaturvedi, Randall B. Meacham and Hari K. Koul
- p38 is a key signaling molecule for H-ras-induced inhibition of gap junction intercellular communication in rat liver epithelial cells / Ki Won Lee, Ji Won Jung, Kyung-Sun Kang and Hyong Joo Lee
- The phosphotyrosine phosphatase [eta] mediates somatostatin inhibition of glioma proliferation via the dephosphorylation of ERK 1/2 / Alessandro Massa, Federica Barbieri, Cinzia Aiello, Rodolfo Iuliano, Sara Arena, Alessandra Pattarozzi, Alessandro Corsaro, Valentina Villa, Alfredo Fusco, Gianluigi Zona, Renato Spaziante, Gennaro Schettini and Tullio Florio
- Blockade by SB203580 of Cyp1a1 induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin, and the possible mechanism : possible involvement of the p38 mitogen-activated protein kinase pathway in shuttling of Ah receptor overexpressed in COS-7 cells / Masahiko Shibazaki, Takahashi Takeuchi, Sohel Ahmed and Hideaki Kikuchi
- Functional characterization of amyloid [beta] precursor protein regulatory elements : rationale for the identification of genetic polymorphism / Debomoy K. Lahiri
- Increased intracellular ionic content is correlated with a decreased perichromatin granule density in old neurons / Carolo Bertoni-Freddari, Patrizia Fattoretti and Manuela Malatesta
- Lack of N1L gene expression results in a significant decrease of vaccinia virus replication in mouse brain / B. Billings, S. A. Smith, Z. Zhang, D. K. Lahiri and G. J. Kotwal
- Increased mitochondrial and nuclear gene expression of cytochrome oxidase subunits I and IV in neuronal aging / Patrizia Fattoretti, Carolo Bertoni-Freddari, Belinda Giorgetti and Marta Balietti
- Role of the APP promoter in Alzheimer's disease : cell type-specific expression of the [beta]-amyloid precursor protein / Debomoy K.
- Lahiri and Yuan-Wen Ge
- Protective effects of oligomers of grape seed polyphenols against [beta]-amyloid-induced oxidative cell death / Mei-Hua Li, Jung-Hee Jang, Buxiang Sun and Young-Joon Surh
- BACE1 overexpression regulates amyloid precursor protein cleavage and interaction with the ShcA adapter / Emanuela Repetto, Claudio Russo, Valentina Venezia, Mario Nizzari, Roger M. Nitsch and Gennaro Schettini
- Apoptotic cell death and amyloid precursor protein signaling in neuroblastoma SH-SY5Y cells / Valentina Venezia, Claudio Russo, Emanuela Repetto, Mario Nizzari, Elisabetta Violani, Pia Carlo, Bianca Marchetti and Gennaro Schettini
- Effect of metal complexes on thioredoxin reductase and the regulation of mitochondrial permeability conditions / M. Bragadin, G. Scutari, A. Folda, A. Bindoli and M. P. Rigobello
- The antiapoptotic protein ICBP90 is a target for protein kinase 2 / Christian Bronner, Marie-Aline Trotzier, Odile Filhol, Claude Cochet, Cecile Rochette-Egly, Marie Scholler-Guinard, Jean-Paul Klein and Marc Mousli
- Docosahexaenoic acid from a cultured microalga inhibits cell growth and induces apoptosis by upregulating Bax/Bcl-2 ratio in human breast carcinoma MCF-7 cells / Lawrence C.-M. Chiu, Elaine Y.-L. Wong and Vincent E. C. Ooi
- Plasma membrane alteration is an early signaling event in doxorubicin-induced apoptosis in the yeast Candida utilis / Ezzatollah Keyhani and Jacqueline Keyhani
- Expression of the insulin-like growth factor-I receptor and proapoptotic Bax and Bak proteins in human colorectal cancer / Mariusz Koda, Joanna Reszec, Mariola Sulkowska, Luiza Kanczuga-Koda and Stanislaw Sulkowski
- Inhibition of B16 mouse melanoma cell growth and induction of apoptotic cell death with 8-chloroadenosine-3',5'-monophosphate and tiazofurin / Lela B. Koricanac, Danijela V. Todorovic, Natasa M. Popovic, Miroslav A. Demajo, Sabera D. Ruzdijic and Aleksandra M. Ristic-Fira
- Alterations in protein expression in HL-60 cells during etoposide-induced apoptosis modulated by the caspase inhibitor ZVAD.fmk / Ruta Navakauskiene, Grazina Treigyte, Jurate Savickiene, Arunas Gineitis and Karl-Eric Magnusson
- Mitochondria of human spermatozoa are preferentially susceptible to apoptosis / Uwe Paasch, Sonja Grunewald, Sylvia Dathe and Hans-Juergen Glander
- Proapoptotic potentials of genistein under growth stimulation by estrogen / Ock Jin Park and Jang-In Shin
- Expression of cell proliferation and apoptosis markers in papillomas and cancers of conjunctiva and eyelid / Joanna Reszec, Mariola Sulkowska, Mariusz Koda, Luiza Kanczuga-Koda and Stanislaw Sulkowski
- Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis / Wei Li and Xi-Ming Yuan
- Suppression of the nuclear factor-[kappa]B activation pathway by spice-derived phytochemicals : reasoning for seasoning / Bharat B. Aggarwal and Shishir Shishodia
- Curcumin stability and its effect on glutathione S-transferase P1-1 mRNA expression in K562 cells / Romain Blasius, Annelyse Duvoix, Franck Morceau, Michael Schnekenburger, Sylvie Delhalle, Estelle Henry, Mario Dicato and Marc Diederich
- Hypoxia/anoxia as signaling for increased alcohol dehydrogenase activity in saffron (Crocus sativus L.) corm. / Ezzatollah Keyhani and Jacqueline Keyhani
- Prevention against oxidative stress of eukaryotic cell membranes by selenium compounds of the rat / A. Kyriakopoulos, K. Bukalis, D. Roethlein, B. Hoppe, A. Graebert and D. Behne
- Effect of dietary restriction on DNA synthesis in vitamin E-deficient rats / Fausto Moroni, Rina Recchioni, Fiorella Marcheselli, Patrizia Fattoretti and Carlo Bertoni-Freddari
- Alternatively spliced protein variants as potential therapeutic targets for male infertility and contraception / Margarida Fardilha, Wenjuan Wu, Rosalia Sa, Sara Fidalgo, Cristina Sousa, Catarina Mota, Odete A. B. da Cruz e Silva and Edgar F. da Cruz e Silva
- Relaxin and phosphodiesterases collaborate during decidualization / Olaf Bartsch and Richard Ivell
- Effects of cyclopentenone prostaglandins on the expression of heme oxygenase-1 in MCF-7 cells / Eun-Hee Kim, Do-Hee Kim, Hye-Kyung Na and Young-Joon Surh
- Inhibition of cyclooxygenase-2 expression and restoration of gap junction intercellular communication in H-ras-transformed rat liver epithelial cells by caffeic acid phenethyl ester / Ki Won Lee, Kyung-Soo Chun, Jeong-Sang Lee, Kyung-Sun Kang, Young-Joon Surh and Hyong Joo Lee
- Comparison of gene expression in intra-abdominal and subcutaneous fat : a study of men with morbid obesity and nonobese men using microarray and proteomics / Finn Edler von Eyben, Jens Peter Kroustrup, Jens Fromholt Larsen and Julio Celis
- GATA-1 : friends, brothers, and coworkers / Franck Morceau, Michael Schnekenburger, Mario Dicato and Marc Diederich
- Tetramethoxy hydroxyflavone p7F downeregulates inflammatory mediators via the inhibition of nuclear factor [kappa]B / Hee-Gu Lee, Hyoson Kim, Won-Keun Oh, Kyung-Ae Yu, Yong-Kyung Choe, Jong-Seog Ahn, Dong-Soo Kim, Soo-Hyun Kim, Charles A. Dinarello, Kilhyoun Kim and Do-Young Yoon
- Sp1 and NF-[kappa]B transcription factor activity in the regulation of the p21 and fasL promoters during promyelocytic leukemia cell monocytic differentiation and its associated apoptosis / Jurate Savickiene, Grazina Treigyte, Augustas Pivoriunas, Ruta Navakauskiene and Karl-Eric Magnusson
- Effects of curcumin (diferuloylmethane) on nuclear factor [kappa]B signaling in interleukin-1[beta]-stimulated chondrocytes / Gundula Schulze-Tanzil, Ali Mobasheri, Judith Sendzik, Thilo John and Mehdi Shakibaei
- The hinge region of the androgen receptor plays a role in proteasome-mediated transcriptional activation / Tamzin Tanner, Frank Claessens and Annemie Haelens
- Polynucleosomal synthesis of poly(ADP-ribose) causes chromatin unfolding as determined by micrococcal nuclease digestion / Maria A. Perez-Lamigueiro and Rafael Alvarez-Gonzalez
- From electrophysiology to chromatin : a bottom-up approach to Angelman syndrome / Bernard Dan, Laurent Servais, Stewart G. Boyd, Joseph Wagstaff and Guy Cheron
- Repetitive treatments of colon HT-29 cells with diallyl disulfide induce a prolonged hyperacetylation of histone H3 K14 / Nathalie Druesne, Anthony Pagniez, Camille Mayeur, Muriel Thomas, Claire Cherbuy, Pierre-Henri Duee, Paule Martel and Catherine Chaumontet
- Thymocyte apoptosis induced by various compounds including YO-2 is accompanied by a change in chromatin structure / Riyo Enomoto, Chiyoko Sugahara, Yuko Tsuda, Yoshio Okada and Eibai Lee
- Defining the chemotherapeutic targets of histone deacetylase inhibitors / Brian Gabrielli, Robyn Warrener, Andrew Burgess and Heather Beamish
- Role of acetylases and deacetylase inhibitors in IRF-1-mediated HIV-1 long terminal repeat transcription / Giulia Marsili, Anna Lisa Remoli, Marco Sgarbanti and Angela Battistini
- Histone structures : targets for modifications by molecular assemblies / James M. Nicholson, Christopher M. Wood, Colin D. Reynolds, Alan Brown, Stanley J. Lambert, Laurent Chantalat and John P. Baldwin
- HDAC-3 participates in the repression of e2f-dependent gene transcription in primary differentiated neurons / Irina Panteleeva, Caroline Rouaux, Yves Larmet, Stephanie Boutillier, Jean-Philippe Loeffler and Anne-Laurence Boutillier
- Plants contain a high number of proteins showing sequence similarity to the animal SUV39H family of histone methyltransferases / Zhong Zhao and Wen-Hui Shen.
