Protein-ligand interactions : methods and applications /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, c2005.
Description:xi, 568 p. : ill. ; 24 cm.
Language:English
Series:Methods in molecular biology, 1064-3745 ; 305
Methods in molecular biology (Clifton, N.J.) ; 305.
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/5628317
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Other authors / contributors:Nienhaus, G. Ulrich (Gerd Ulrich)
ISBN:1588293726 (alk. paper)
Notes:Includes bibliographical references and index.
Table of Contents:
  • Preface
  • Contributors
  • 1. Isothermal Titration Calorimetry
  • 2. Direct Optical Detection of Protein-Ligand Interactions
  • 3. Label-Free Detection of Protein-Ligand Interactions by the Quartz Crystal Microbalance
  • 4. Measurement of Solvent Accessibility at Protein-Protein Interfaces
  • 5. Hydrophobic Interaction Chromatography: Harnessing Multivalent Protein-Surface Interactions for Purification Procedures
  • 6. Sedimentation Velocity Method in the Analytical Ultracentrifuge for the Study of Protein-Protein Interactions
  • 7. Protein-Ligand Interaction Probed by Time-Resolved Crystallography
  • 8. X-Ray Crystallography of Protein-Ligand Interactions
  • 9. Combined Use of XAFS and Crystallography for Studying Protein-Ligand Interactions in Metalloproteins
  • 10. NMR Studies of Protein-Ligand Interactions
  • 11. Probing Heme Protein-Ligand Interactions by UV/Visible Absorption Spectroscopy
  • 12. Ultrafast Time-Resolved IR Studies of Protein-Ligand Interactions
  • 13. Monitoring Protein-Ligand Interactions by Time-Resolved FTIR Difference Spectroscopy
  • 14. Proteins in Motion: Resonance Raman Spectroscopy as a Probe of Functional Intermediates
  • 15. Fluorescence Polarization/Anisotropy Approaches to Study Protein-Ligand Interactions: Effects of Errors and Uncertainties
  • 16. Ligand Binding With Stopped-Flow Rapid Mixing
  • 17. Circular Dichroism Spectroscopy for the Study of Protein-Ligand Interactions
  • 18. High-Throughput Screening of Interactions Between G Protein-Coupled Receptors and Ligands Using Confocal Optics Microscopy
  • 19. Single-Molecule Study of Protein-Protein and Protein-DNA Interaction Dynamics
  • 20. Application of Fluorescence Correlation Spectroscopy to Hapten-Antibody Binding
  • 21. Atomic Force Microscopy Measurements of Protein-Ligand Interactions on Living Cells
  • 22. Computer Simulation of Protein-Ligand Interactions: Challenges and Applications
  • 23. Force Probe Molecular Dynamics Simulations
  • 24. Study of Ligand-Protein Interactions by Means of Density Functional Theory and First-Principles Molecular Dynamics
  • Index