Pharmacogenomics : methods and protocols /
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| Imprint: | Totowa, N.J. : Humana Press, c2005. |
|---|---|
| Description: | x, 214 p. : ill. ; 24 cm. |
| Language: | English |
| Series: | Methods in molecular biology, 1064-3745 ; 311 Methods in molecular biology (Clifton, N.J.) ; v. 311. |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/5729090 |
Table of Contents:
- Preface
- Contributors
- Part I. History and Overview
- 1. Pharmacogenomics: Historical Perspective and Current Status
- Part II. Functional Analysis of Gene Variation
- 2. Transfection Assays With Allele-Specific Constructs: Functional Analysis of UDP-Glucuronosyltransferase Variants
- 3. Snapshot of the Allele-Specific Variation in Human Gene Expression
- 4. Genome-Wide Analysis of Allele-Specific Gene Expression Using Oligo Microarrays
- 5. HaploChIP: An In Vivo Assay
- Part III. Genotyping Techniques
- 6. Aspects Influencing Genotyping Method Selection
- 7. Denaturing High-Performance Liquid Chromatography for Mutation Detection and Genotyping
- 8. Pyrosequencing of Clinically Relevant Polymorphisms
- 9. Kinetic Fluorescence-Quenching Detection Assay for Allele Frequency Estimation
- 10. Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
- 11. Fluorescence-Based Fragment Size Analysis
- 12. Single-Nucleotide Polymorphism Genotyping in DNA Pools
- 13. TaqMan Genotyping of Insertion/Deletion Polymorphisms
- Part IV. Management of Pharmacogenomic Information
- 14. PharmGKB: The Pharmacogenetics and Pharmacogenomics Knowledge Base
- 15. Systems for the Management of Pharmacogenomic Information
- Index
