The serotonin receptors : from molecular pharmacology to human therapeutics /
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| Imprint: | Totowa, N.J. : Humana Press, c2006. |
|---|---|
| Description: | xvii, 618 p. : ill. ; 24 cm. |
| Language: | English |
| Series: | The receptors |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/6058434 |
Table of Contents:
- Preface
- Contributors
- Color Plate
- 1. Molecular Biology and Genomic Organization of G Protein-Coupled Serotonin Receptors
- 2. Structure and Function Reveal Insights in the Pharmacology of 5-HT Receptor Subtypes
- 3. Polymorphic and Posttranscriptional Modifications of 5-HT Receptor Structure: Functional and Pathological Implications
- 4. Strategies for the Development of Selective Serotonergic Agents
- 5. 5-HT Receptor Signal Transduction Pathways
- 6. Agonist-Directed Trafficking of 5-HT Receptor-Mediated Signal Transduction
- 7. Identification of 5-HT2 and 5-HT4 Receptor-Interacting Proteins: A Proteomic Approach
- 8. 5-HT Receptor-Associated Proteins (FRAPs): Relevance for Targeting, Trafficking, and Signal Transduction
- 9. Cellular and Subcellular Localization of Serotonin Receptors in the Central Nervous System
- 10. Chemical Neuroanatomy of 5-HT Receptor Subtypes in the Mammalian Brain
- 11. Modulation of the Neuronal Activity and Neurotransmitter Release by 5-HT1A and 5-HT1B/1D Receptors
- 12. Electrophysiology of 5-HT2A Receptors and Relevance for Hallucinogen and Atypical Antipsychotic Drug Actions
- 13. The Emergence of 5-HT2B Receptors as Targets to Avoid in Designing and Refining Pharmaceuticals
- 14. The 5-HT3 Receptor
- 15. 5-HT3 and 5-HT4 Receptors as Targets for Drug Discovery for Dementia
- 16. Electrophysiological Properties of Gas-Coupled 5-HT Receptors (5-HT4, 5-HT6, 5-HT7)
- 17. 5-HT6 Receptors as Targets for the Treatment of Cognitive Deficits in Schizophrenia
- 18. 5-HT7 Receptors as Favorable Pharmacological Targets for Drug Discovery
- 19. Serotonin System Gene Knockouts: A Story of Mice With Implications for Man
- 20. Effects of Serotonin-Related Gene Deletion on Measures of Anxiety, Depression, and Neurotransmission
- Index
