Protein misfolding, aggregation and conformational diseases /

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Bibliographic Details
Imprint:New York : Springer, c2006-2007.
Description:2 v. : ill. (some col.) ; 25 cm.
Language:English
Series:Protein reviews ; v. 4, 6
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/6097045
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Other authors / contributors:Uversky, Vladimir N.
Fink, Anthony L., 1943-
ISBN:038725918X (pt. A)
9780387259185 (pt. A)
038736529X (pt. B)
9780387365299 (pt. B)
0387365346 (e-isbn)
9780387365343 (e-isbn)
Notes:Includes bibliographical references and index.
Table of Contents:
  • 1. Structural and conformational prerequisites of amyloidogenesis / Vladimir N. Uversky, Ariel Fernandez and Anthony L. Fink
  • 2. The generic nature of protein folding and misfolding / Christopher M. Dobson
  • 3. Relative importance of hydrophobicity, net charge, and secondary structure propensities in protein aggregation / Febrizio Chiti
  • 4. Cytotoxic intermediates in the fibrillation pathway : a[beta] oligomers in Alzheimer's disease as a case study / William L. Klein
  • 5. Glycosaminoglycans, proteoglycans, and conformational disorders / Gregory J. Cole and I.-Hsuan Liu
  • 6. Apolipoproteins in different amyloidoses / Marcin Sadowski and Thomas Wisniewski
  • 7. Oxidative stress and protein deposition disease / Joseph R. Mazzulli, Roberto Hodara, Summer Lind and Harry Ischiropoulos
  • 8. Chaperone and conformational disorders
  • Chaperone suppression of aggregated protein toxicity / Jennifer L. Wacker and Paul J. Muchowski
  • Mechanisms of active solubilization of stable protein aggregates by molecular chaperones / Pierre Goloubinoff and Anat Peres Ben-Zvi
  • 9. The aggresome : proteasomes, inclusion bodies, and protein aggregation / Jennifer A. Johnston
  • 10. Protein aggregation, ion channel formation, and membrane damage / Bruce L. Kagan
  • 11. Visualization of protein deposits in vivo
  • Congo red staining of amyloid : improvements and practical guide for a more precise diagnosis of amyloid and the different amyloidoses / Reinhold P. Linke
  • Immunohistological study of experimental murine AA amyloidosis / Mie Kuroiwa, Kimiko Aoki and Naotaka Izumiyama
  • 12. Visualization of protein deposits in vitro
  • Reporters of amyloid structure / Harry LeVine III
  • Three-dimensional structural analysis of amyloid fibrils by electron microscopy / Sara Cohen-Krausz and Helen R. Saibil
  • Atomic force microscopy / Justin Legieiter and Tomasz Kowalewski
  • Direct observation of amyloid fibril growth monitored by total internal reflection fluorescence microscopy / Tadato Ban and Yuji Goto
  • 13. Animal and cell models of human neurodegenerative disorders
  • Drosophila and C. elegans models of human age-associated neurodegenerative diseases / Julide Bilen and Nancy M. Bonini
  • Genetically engineered mouse models of neurodegenerative disorders / Eliezer Masliah and Leslie Crews.
  • pt. A. Protein aggregation and conformational diseases
  • pt. B. Molecular mechanisms of conformational diseases.