Vitamin D analogs in cancer prevention and therapy /

Saved in:
Bibliographic Details
Imprint:Berlin ; New York : Springer, c2003.
Description:viii,432 p. : ill. (some col.) ; 24 cm.
Language:English
Series:Recent results in cancer research, 0080-0015 ; 164
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/6118193
Hidden Bibliographic Details
Other authors / contributors:Reichrath, J. (Jörg), 1962-
Friedrich, M. (Michael), 1966-
Tilgen, W. (Wolfgang), 1944-
ISBN:3540002901 (alk. paper)
Notes:Includes bibliographical references and index.
Table of Contents:
  • 1. Molecular Biology of Vitamin D
  • Evolution and Function of Vitamin D / Michael F. Holick
  • Current Understanding of the Function of the Nuclear Vitamin D Receptor in Response to Its Natural and Synthetic Ligands / Carsten Carlberg
  • Approaches to Evaluating the Association of Vitamin D Receptor Gene Polymorphisms with Breast Cancer Risk / Michelle Guy, Lorraine C. Lowe, Deborah Bretherton-Watt, Janine L. Mansi and Kay W. Colston
  • Ligand Structure-Function Relationships in the Vitamin D Endocrine System from the Perspective of Drug Development (Including Cancer Treatment) / Anthony W. Norman, Mathew T. Mizwicki and William H. Okamura
  • Antiproliferative Signalling by 1,25(OH)[subscript 2]D[subscript 3] in Prostate and Breast Cancer Is Suppressed by a Mechanism Involving Histone Deacetylation / Claire M. Banwel, Rena Singh, Paul M. Stewart, Milan R. Uskokovic and Moray J. Campbell
  • Mechanisms Implicated in the Growth Regulatory Effects of Vitamin D Compounds in Breast Cancer Cells / Lorraine Lowe, Christina Mork Hansen, Siddhika Senaratne and Kay W. Colston
  • Squamous Cell Carcinomas Fail to Respond to the Prodifferentiating Actions of 1,25(OH)[subscript 2]D: Why? / Daniel D. Bikle, Zhongjian Xie, Dean Ng, Chia-Ling Tu and Yuko Oda
  • A Novel Vitamin D-Regulated Immediate-Early Gene, IEX-1, Alters Cellular Growth and Apoptosis / Rajiv Kumar, Mark R. Pittelkow, Jeffrey L. Salisbury, Joseph P. Grande, Hee-Jeong Im, Kathrin A. Feldmann and David Schilling
  • Extrarenal Sites of Calcitriol Synthesis: The Particular Role of the Skin / Bodo Lehmann and Michael Meurer
  • Cultured Rat Growth Plate Chondrocytes Express Low Levels of 1[alpha]-Hydroxylase / Lutz Weber, Ulrike Hugel, Jorg Reichrath, Hauke Sieverts, Otto Mehls and Gunter Klaus
  • Gene Amplification and Splice Variants of 25-Hydroxyvitamin D[subscript 3] 1, [alpha]-Hydroxylase (CYP27B1) in Glioblastoma Multiforme - A Possible Role in Tumor Progression? / Britta Diesel, Ulrike Fischer and Eckart Meese
  • Regulation of the 25-Hydroxyvitamin D-1[alpha]-Hydroxylase Gene and Its Splice Variant / John N. Flanagan, Lilin Wang, Vin Tangpricha, Jorg Reichrath, Tai C. Chen and Michael F. Holick
  • Combination of Vitamin D Metabolites with Selective Inhibitors of Vitamin D Metabolism / Inge Schuster, Helmut Egger, Gerda Herzig, G. Satyanarayana Reddy and Georg Vorisek
  • Importance Of Cytochrome P450-Mediated Metabolism in the Mechanism of Action of Vitamin D Analogs / Sonoko Masuda, Mian Gao, Anqi Zhang, Martin Kaufmann and Glenville Jones
  • 2. The Vitamin D System in Cancer
  • The Role of Vitamin D in Prostate Cancer / Aruna V. Krishnan, Donna M. Peehl and David Feldman
  • Vitamin D Autocrine System and Prostate Cancer / Lilin Wang, Lyman W. Whitlatch, John N. Flanagan, Michael F. Holick and Tai C. Chen
  • Analysis of the Vitamin D System in Cervical Carcinomas, Breast Cancer and Ovarian Cancer / Michael Friedrich, Leyla Rafi, Tanja Mitschele, Wolfgang Tilgen, Werner Schmidt and Jorg Reichrath
  • Short-Chain Fatty Acids and Colon Cancer Cells: The Vitamin D Receptor - Butyrate Connection / Tanja Gaschott and Jurgen Stein
  • Analysis of the Vitamin D system in Cutaneous Malignancies / Jorn Kamradt, Leyla Rafi, Tanja Mitschele, Viktor Meineke, Barbara C. Gartner, Wolfgang Tilgen, Michael F. Holick and Jorg Reichrath
  • 3. Antitumor Effects of Vitamin D Analogs
  • Evaluation of Vitamin D Analogs as Therapeutic Agents for Prostate Cancer / Tai C. Chen, Michael F. Holick, Bal L. Lokeshwar, Kerry L. Burnstein and Gary G. Schwartz
  • Design, Synthesis, and Biological Studies of the A-Ring-Modified 1,25-Dihydroxyvitamin D3 Analogs / Hiroaki Takayama, Atsushi Kittaka, Toshie Fujishima and Yoshitomo Suhara
  • Induction of Apoptosis by Vitamin D Metabolites and Analogs in a Glioma Cell Line / Josef Elias, Brigitte Marian, Christa Edling, Bodo Lachmann, Christian R. Noe, Rolf Schulte-Hermann and Inge Schuster
  • Vitamin D Analogs and Breast Cancer / James O'Kelly and H. Phillip Koeffler
  • A Low-Calcemic Vitamin D Analog (Ro 25-4020) Inhibits the Growth of LNCaP Human Prostate Cancer Cells with Increased Potency by Producing an Active 24-Oxo Metabolite (Ro 29-9970) / Srilatha Swami, Xiao-Yan Zhao, Stephen Sarabia, Mei-Ling Siu-Caldera, Milan Uskokovic, Satya G. Reddy and David Feldman
  • Prospects for Vitamin D receptor Modulators as Candidate Drugs for Cancer and (Auto)immune Diseases / Roger Bouillon, Annemieke Verstuyf, Lieve Verlinden, Guy Eelen and Chantal Mathieu
  • The Role of Reactive Oxygen Species in the Anticancer Activity of Vitamin D / Amiram Ravid and Ruth Koren
  • 4. Vitamin D in Cancer Prevention
  • Ecologic Studies of Solar UV-B Radiation and Cancer Mortality Rates / William B. Grant
  • Phytoestrogens and 17[beta]-Estradiol Influence Vitamin D Metabolism and Receptor Expression - Relevance for Colon Cancer Prevention / Daniel Lechner and Heide S. Cross
  • Efficacy and Mechanism of Action of 1[alpha]-hydroxy-24-ethyl-Cholecalciferol (1[alpha][OH]D5) in Breast Cancer Prevention and Therapy / Erum A. Hussain, Rajeshwari R. Mehta, Rahul Ray, Tapas K. Das Gupta and Rajendra G. Mehta
  • Regulation of Extrarenal Vitamin D Metabolism as a Tool for Colon and Prostate Cancer Prevention / Heide S. Cross, Eniko Kallay, Hesso Farhan, Tina Weiland and Theresa Manhardt
  • Modulation of X-ray-Induced Apoptosis in Human Keratinocytes (HaCaT) by 1,25-Dihydroxyvitamin D[subscript 3] / Viktor Meineke, Carolina Pfaffendorf, Michaela Schinn, Wolfgang Tilgen, Artur Mayerhofer, Nicola Dimitrijevic, Dirk van Beuningen and Jorg Reichrath.