Gene therapy for cancer /

Saved in:
Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, c2007.
Description:xi, 469 p. : ill. (some col.) ; 27 cm.
Language:English
Series:Cancer drug discovery and development
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/6202680
Hidden Bibliographic Details
Other authors / contributors:Hunt, Kelly K.
Vorburger, Stephan A.
Swisher, Stephen G.
ISBN:1588294722 (alk. paper)
9781588294722 (alk. paper)
Notes:Includes bibliographical references and index.
Table of Contents:
  • Preface
  • Contributors
  • I. Vectors
  • 1. Adenovector-Mediated Cancer Gene Therapy
  • 2. Efficacy, Toxicity, and Immunogenicity of Adenoviral Vectors
  • 3. Lentiviral and Retroviral Vector Systems
  • 4. Vaccinia and Pox-Virus
  • 5. Herpes Simplex Virus as a Therapy for Cancer
  • 6. Alphavirus Vectors for Gene Therapy Applications
  • 7. Vesicular Stomatitis Virus and RNA Viruses as Gene Therapy Vectors
  • 8. Parvovirus Vectors
  • 9. Nonviral Vector Systems
  • II. Gene Therapy Approaches
  • 10. Oncogenes, Tumor Suppressor Genes, and Apoptosis-Inducing Genes Utilized in Cancer Gene Therapy
  • 11. Gene Silencing Therapy Against Cancer
  • 12. Tumor Targeting-Retargeted Adenovirus
  • 13. Oncolytic Herpes Simplex for Gene Therapy in Preclinical and Clinical Trials
  • 14. Cytokine Gene Therapy for Genitourinary Cancer
  • 15. Combination of Gene Therapy with Radiation
  • 16. Gene Transfer for Chemoprotection and Enrichment of Hematopoietic Stem Cells
  • 17. Nonviral Genetic Vaccines for Cancer
  • 18. Gene Therapy Targeted at Angiogenesis and Lymphangiogenesis for Cancer Treatment
  • 19. Tumor-Specific Replicating Adenoviruses: [Delta] 24 for Human Gliomas
  • III. Clinical Applications
  • 20. Problems, Side Effects, and Disappointments in Clinical Cancer Gene Therapy
  • 21. Trials and Tribulations in Developing Clinical Trials of Gene Therapy: E1A for Breast or Ovarian Cancer
  • 22. Phase I Clinical Experience with Intravenous Administration of PV701, an Oncolytic Virus
  • 23. MDA-7/IL-24 as a Multi-Modality Therapy for Cancer
  • 24. Development of Therapeutic Genes for Breast Cancer Treatment
  • 25. Steps in a Translational Cancer Gene Therapy Trial
  • Index