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061020s2006 gw a b 001 0 eng |
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|a GBA643472
|2 bnb
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|a 013455831
|2 Uk
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| 020 |
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|a 3527312919
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|a 9783527312917
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3 |
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|a 9783527312917
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|a UKM
|c UKM
|d BAKER
|d OHX
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|2 22
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|a RM301.25
|b .F72 2006
|
| 245 |
0 |
0 |
|a Fragment-based approaches in drug discovery /
|c edited by Wolfgang Jahnke and Daniel A. Erlanson.
|
| 260 |
|
|
|a Weinheim :
|b Wiley-VCH ;
|a [Chichester :
|b John Wiley, distributor],
|c c2006.
|
| 300 |
|
|
|a xxii, 369 p. :
|b ill. (some col.) ;
|c 25 cm.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|0 http://id.loc.gov/vocabulary/contentTypes/txt
|
| 337 |
|
|
|a unmediated
|b n
|2 rdamedia
|0 http://id.loc.gov/vocabulary/mediaTypes/n
|
| 338 |
|
|
|a volume
|b nc
|2 rdacarrier
|0 http://id.loc.gov/vocabulary/carriers/nc
|
| 440 |
|
0 |
|a Methods and principles in medicinal chemistry ;
|v 34
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 505 |
0 |
0 |
|g 1.
|t The concept of fragment-based drug discovery /
|r Daniel A. Erlanson and Wolfgang Jahnke --
|g 2.
|t Multivalency in ligand design /
|r Vijay M. Krishnamurthy, Lara A. Estroff and George M. Whitesides --
|g 3.
|t Entropic consequences of linking ligands /
|r Christopher W. Murray and Marcel L. Verdonk --
|g 4.
|t Location of binding sites on proteins by the multiple solvent crystal structure method /
|r Dagmar Ringe and Carla Mattos --
|g 5.
|t Cheminformatics approaches to fragment-based lead discovery /
|r Tudor I. Oprea and Jeffrey M. Blaney --
|g 6.
|t Structural fragments in marketed oral drugs /
|r Michal Vieth and Miles Siegel --
|g 7.
|t Fragment docking to proteins with the multi-copy simultaneous search methodology /
|r Collin M. Stultz and Martin Karplus --
|g 8.
|t NMR-guided fragment assembly /
|r Daniel S. Sem --
|g 9.
|t SAR by NMR : an analysis of potency gains realized through fragment-linking and fragment-elaboration strategies for lead generation /
|r Philip J. Hajduk, Jeffrey R. Huth and Chaohong Sun --
|g 10.
|t Pyramid : an integrated platform for fragment-based drug discovery /
|r Thomas G. Davies, Rob L. M. van Montfort, Glyn Williams and Harren Jhoti --
|g 11.
|t Fragment-based lead discovery and optimization using X-ray crystallography, computational chemistry, and high-throughput organic synthesis /
|r Jeff Blaney, Vicki Nienaber and Stephen K. Burley --
|g 12.
|t Synergistic use of protein crystallography and solution-phase NMR spectroscopy in structure-based drug design : strategies and tactics /
|r Cele Abad-Zapatero, Geoffrey F. Stamper and Vincent S. Stoll --
|g 13.
|t Ligand SAR using electrospray ionization mass spectrometry /
|r Richard H. Griffey and Eric E. Swayze --
|g 14.
|t Tethering /
|r Daniel A. Erlanson, Marcus D. Ballinger and James A. Wells --
|g 15.
|t Click chemistry for drug discovery /
|r Stefanie Roper and Hartmuth C. Kolb --
|g 16.
|t Dynamic combinatorial diversity in drug discovery /
|r Matthias Hochgurtel and Jean-Marie Lehn.
|
| 650 |
|
0 |
|a Drug development.
|0 http://id.loc.gov/authorities/subjects/sh97007921
|
| 650 |
|
0 |
|a Ligands (Biochemistry)
|0 http://id.loc.gov/authorities/subjects/sh89002279
|
| 650 |
|
7 |
|a Drug development.
|2 fast
|0 http://id.worldcat.org/fast/fst00898670
|
| 650 |
|
7 |
|a Ligands (Biochemistry)
|2 fast
|0 http://id.worldcat.org/fast/fst00998471
|
| 700 |
1 |
|
|a Jahnke, Wolfgang.
|0 http://id.loc.gov/authorities/names/nb2006018734
|1 http://viaf.org/viaf/22863089
|
| 700 |
1 |
|
|a Erlanson, Daniel A.
|0 http://id.loc.gov/authorities/names/nb2006018735
|1 http://viaf.org/viaf/273879424
|
| 901 |
|
|
|a ToCBNA
|
| 903 |
|
|
|a HeVa
|
| 035 |
|
|
|a (OCoLC)67873894
|
| 929 |
|
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|a cat
|
| 999 |
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|i 6c9f60c4-f18a-5013-b903-3bf3c880c362
|s cc61eba0-8a66-51eb-97ea-0e83947ad9c4
|
| 928 |
|
|
|t Library of Congress classification
|a RS420 .F73 2006
|l JCL
|c JCL-Sci
|i 5219976
|
| 927 |
|
|
|t Library of Congress classification
|a RS420 .F73 2006
|l JCL
|c JCL-Sci
|e CRERAR
|b 75701483
|i 8118071
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