Linkage disequilibrium and association mapping : analysis and applications /

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Bibliographic Details
Imprint:	Totowa, N.J. : Humana Press, c2007.
Description:	xiv, 255 p. : ill. ; 24 cm.
Language:	English
Series:	Methods in molecular biology ; 376 Methods in molecular biology (Clifton, N.J.) ; v. 376.
Subject:	Genomics -- Statistical methods. Gene mapping. Linkage Disequilibrium. Chromosome Mapping. Gene mapping. Genomics -- Statistical methods.
Format:	Print Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/6611675

Hidden Bibliographic Details
Other authors / contributors:	Collins, A. (Andrew)
ISBN:	1588296695 (alk. paper) 9781588296696 (alk. paper)
Notes:	Includes bibliographical references and index.

Table of Contents:

Dedication
Preface
Contributors
1. Linkage Disequilibrium and Association Mapping: An Introduction
2. A History of Association Mapping
3. Linkage Disequilibrium Maps and Location Databases
4. LDMAP: The Construction of High-Resolution Linkage Disequilibrium Maps of the Human Genome
5. Linkage Disequilibrium as a Tool for Detecting Signatures of Natural Selection
6. The Genetic Basis of Complex Traits: Rare Variants or "Common Gene, Common Disease"?
7. Linkage Disequilibrium Mapping for Complex Disease Genes
8. Linkage Disequilibrium Maps and Disease-Association Mapping
9. Coalescent Methods for Fine-Scale Disease-Gene MappingAndrew P. Morris
10. Family-Based Linkage Disequilibrium Tests Using General Pedigrees
11. Association Studies Using Familial Cases: An Efficient Strategy for Identifying Low-Penetrance Disease Alleles
12. Association Mapping Using Pooled DNA
13. Selecting Single-Nucleotide Polymorphisms for Association Studies With SNPbrowser Software
14. Avoiding False Discoveries in Association Studies
15. Gene Mapping in Asthma-Related Traits
16. Identifying Susceptibility Variants for Type 2 Diabetes
Index

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