Ancestral sequence reconstruction /

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Bibliographic Details
Imprint:Oxford : Oxford University Press, 2007.
Description:xiii, 252 p. : ill. ; 25 cm.
Language:English
Subject:
Format: E-Resource Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/6635835
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Other authors / contributors:Liberles, David A.
ISBN:9780199299188 (hbk.)
0199299188 (hbk.)
Notes:Includes bibliographical references and index.
Table of Contents:
  • 1. The Early Days of Paleogenomics, Connecting Molecules to the Planet
  • 2. Ancestral Sequence Reconstruction as a Tool to Understand Natural History and Guide Synthetic Biology: Realizing and Extending the Vision of Zuckerkandl and Pauling
  • 3. Linking Sequence to Function in Drug Design with Ancestral Sequence Reconstruction
  • 4. Probabilistic Models and Their Impact on the Accuracy of Reconstructed Ancestral Sequences, Tal Pupko, Adi Doron-Faigenboim
  • 5. Probabilistic Ancestral Sequences Based on the Markovian Model of Evolution- Algorithms and Applications
  • 6. Estimating the History of Mutations on a Phylogeny
  • 7. Coarse Projections of the Protein-Mutational Fitness Landscape
  • 8. Dealing with Uncertainty in Ancestral Sequence Reconstruction: Sampling from the Posterior Distribution
  • 9. Evolutionary Properties of Sequences and Ancestral State Reconstruction
  • 10. Reconstructing the Ancestral Eukaryote- Lessons from the Past
  • 11. Using Ancestral Sequence Inference to Determine the Trend of Functional Divergence After Gene Duplication
  • 12. Reconstruction of Ancestral Proteomes
  • 13. Computational Reconstruction of Ancestral Genomic Regions from Evolutionarily Conserved Gene Clusters
  • 14. Experimental Resurrection of Ancient Biomolecules: Gene Synthesis, Heterologous Protein Expression, and Functional Assays
  • 15. Dealing with Model Uncertainty in Reconstructing Ancestral Proteins in the Laboratory: Examples from Ancestral Visual Pigments and GFP-like Proteins
  • 16. Unraveling the Evolution of Complexity by Resurrecting Ancient Genes
  • 17. A Thermophilic Last Universal Ancestor Inferred from its Estimated Amino Acid Composition
  • 18. The Resurrection of Ribonucleases from Mammals. From Ecology to Medicine
  • 19. Evolution of Specificity and Diversity,