Immunogenetics of autoimmune disease /
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Imprint: | Georgetown, Tex. : Landes Bioscience/Eurekah.com ; New York : Springer Science+Business Media, c2006. |
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Description: | 158 p. : ill. (some col.) ; 24 cm. |
Language: | English |
Series: | Medical intelligence unit Medical intelligence unit (Unnumbered : 2003) |
Subject: | |
Format: | Print Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/6647621 |
Table of Contents:
- Preface
- 1. HLA and Autoimmunity: Structural Basis of Immune Recognition
- General Structural Features of MHC Class II Molecules
- Structural Properties of HLA-DR Molecules Associated with Human Autoimmune Diseases
- Structure and Function of HLA-DQ Molecules That Confer Susceptibility to Type 1 Diabetes and Celiac Disease
- Presentation of Deamidated Gliadin Peptides by HLA-DQ8 and HLA-DQ2 in Celiac Disease
- Disease-Associated MHC Class II Molecules and Thymic Repertoire Selection
- 2. Genomic Variation and Autoimmune Disease
- Study Design and Methods of Linkage Analysis
- Study Design for Association Analysis
- Population-Based Association Analysis Methods
- Genetic Markers and Detection Methods
- Genetic Studies of Autoimmune Disorders
- New Approaches to Genome Wide Screening to Detect Disease Associations
- 3. Endocrine Diseases: Type I Diabetes Mellitus
- The HLA Region in T1D Susceptibility
- Non HLA Genes in T1D Susceptibility
- Additional Candidate Genes
- Vitamin D Receptor
- EIF2AK3
- PTPN22
- SUMO4
- 4. Endocrine Diseases: Graves' and Hashimoto's Diseases
- Genetic Epidemiology of AITD
- Susceptibility Genes in AITD Immune Related Genes
- Thyroid Associated Genes
- The Effect of Ethnicity on the Development of AITD
- Mechanisms by Which Genes Can Induce Thyroid Autoimmunity
- 5. Central and Peripheral Nervous System Diseases
- Multiple Sclerosis
- Myasthenia Gravis
- Guillain Barre Syndrome
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
- Narcolepsy
- Serological Typing Studies
- HLA-DQB1*0602
- Complementation of HLA-DQA1 and DQB1
- Sequencing of HLA Alleles
- Other HLA Protecting or Favorizing Genes
- 6. Immunogenetics of Rheumatoid Arthritis, Systemic Sclerosis and Systemic Lupus Erythematosus
- Rheumatoid Arthritis (RA)
- Scleroderma and Systemic Sclerosis (SSc)
- HLA Associations with SSc and SSc Related Autoantibodies
- Systemic Lupus Erythematosus (SLE)
- 7. Gastroenterologic and Hepatic Diseases
- Inflammatory Bowel Diseases
- Celiac Disease
- Autoimmune Hepatitis
- 8. Inflammatory Myopathies: Dermatomyositis, Polymyositis and Inclusion Body Myositis
- Clinical Aspects
- Histopathology
- Immunopathogenesis
- 9. Hematologic Diseases: Autoimmune Hemolytic Anemia and Immune Thrombocytopenic Purpura
- Autoimmune Hemolytic Anemia
- Immune Thrombocytopenic Purpura
- Genetic Control of AEA in AIHA
- HLA Susceptibility Genes and ITP
- Genetic Alterations in the Control of T Cell Activation
- Defective Lymphocyte Apoptosis
- Fc[gamma] Receptor Polymorphisms in ITP
- Erythrocyte CD47 and Autoimmune Hemolytic Anemia
- 10. Genetics of Autoimmune Myocarditis
- The Clinical Impact of Autoimmune Heart Disease
- Coxsackievirus B3 (CB3) Induced Cardiomyopathy Is an Autoimmune Disease
- Genetic Influence on Autoimmune Heart Disease
- Study of Mechanism of Autoimmunity through Identification of Susceptibility Genes
- Loci Which Influence Autoimmune Myocarditis Are Also Involved in Other Autoimmune Diseases in the A vs. C57BL/6 (B) Murine Model
- Sensitivity to Apoptosis May Influence Development of Autoimmune Myocarditis
- Autoimmune Myocarditis in the DBA/2 Mouse Model-Same Phenotypic Disease via Different Mechanisms and Different Loci
- Index