Nucleic acid-metal ion interactions /

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Bibliographic Details
Imprint:New York : Wiley, c1980.
Description:ix, 256 p. : ill. ; 24 cm.
Language:English
Series:Metal ions in biology v. 1
Subject:
Format: Print Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/710440
Hidden Bibliographic Details
Other authors / contributors:Spiro, Thomas G., 1935-
ISBN:0471043990
Notes:"A Wiley-interscience publication."
Includes bibliographical references and index.
Description
Summary:First volume in this series which surveys new insights and directions emerging from research into the structural chemistry operating at the biological sites where metal ions are found. Examines a newly emergent focus of research activity-interactions of metal ions with nucleic acids. Selected papers describe important ongoing investigations in five key areas: discovery and therapeutic application of the anticancer properties of cis-dichlorodiammine platinum (II) and related metal complexes; possible modes of action of platinum anticancer agents, also uses of heavy metal complex in probing structure of nucleic acids; metals as mutagens and carcinogens; metal ion interactions with transfer RNA (the one nucleic acid having high-resolution three-dimensional crystal structures); and modes whereby metal ions may interact with constituents of nucleic acids.
Item Description:"A Wiley-interscience publication."
Physical Description:ix, 256 p. : ill. ; 24 cm.
Bibliography:Includes bibliographical references and index.
ISBN:0471043990