Platelet-vessel wall interactions in hemostasis and thrombosis /
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| Author / Creator: | Rumbaut, Rolando E. |
|---|---|
| Imprint: | San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan & Claypool, c2010. |
| Description: | 1 electronic text (viii, 67 p. : ill.) : digital file. |
| Language: | English |
| Series: | Synthesis lectures on integrated systems physiology, from molecules to function, 1947-9468 ; # 4 Colloquium series on integrated systems physiology, from molecule to function, # 4. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/8512928 |
MARC
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| 024 | 7 | |a 10.4199/C00007ED1V01Y201002ISP004 |2 doi | |
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| 082 | 0 | 4 | |a 616.135 |2 22 |
| 100 | 1 | |a Rumbaut, Rolando E. | |
| 245 | 1 | 0 | |a Platelet-vessel wall interactions in hemostasis and thrombosis / |c Rolando E. Rumbaut and Perumal Thiagarajan. |
| 260 | |a San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : |b Morgan & Claypool, |c c2010. | ||
| 300 | |a 1 electronic text (viii, 67 p. : ill.) : |b digital file. | ||
| 336 | |a text |b txt |2 rdacontent |0 http://id.loc.gov/vocabulary/contentTypes/txt | ||
| 337 | |a computer |b c |2 rdamedia |0 http://id.loc.gov/vocabulary/mediaTypes/c | ||
| 338 | |a online resource |b cr |2 rdacarrier |0 http://id.loc.gov/vocabulary/carriers/cr | ||
| 490 | 1 | |a Synthesis lectures on integrated systems physiology, from molecules to function, |x 1947-9468 ; |v # 4 | |
| 500 | |a Title from PDF t.p. (viewed on March 17, 2010). | ||
| 500 | |a Series from website. | ||
| 504 | |a Includes bibliographical references (p. 45-67). | ||
| 505 | 0 | |a 1. Introduction -- 2. General characteristics of platelets -- Overview -- Platelet granules -- Alpha granules -- Dense granules -- Lysosomes -- Platelet adhesion molecules -- P-selectin -- Glycoprotein Ib/IX/V (GPIb/IX/V) -- Glycoprotein IIb/IIIa (GP IIb/IIIa) -- Collagen receptors -- G-protein-coupled receptors -- Thrombin -- Adenosine diphosphate (ADP) and adenosine triphosphate (ATP) -- Prostanoids -- | |
| 505 | 8 | |a 3. Platelet adhesion to vascular walls -- Adhesion to subendothelium following vascular injury -- Von Willebrand factor (vWF) -- Collagen -- Other subendothelial components -- Endogenous mechanisms preventing platelet adhesion to endothelium -- Nitric oxide -- Prostacyclin -- Ecto-adenosine diphosphatase (ADPase) -- Endothelial surface layer -- Mechanisms of platelet adhesion to endothelium -- Endothelial P-selectin-dependent mechanisms -- Endothelial vWF-dependent mechanisms -- Other mechanisms -- | |
| 505 | 8 | |a 4. Platelet aggregation -- Mechanisms of platelet aggregation -- Monitoring of platelet aggregation -- Ex vivo monitoring: platelet aggregometry -- In vivo monitoring of platelet aggregation -- | |
| 505 | 8 | |a 5. Platelet recruitment and blood coagulation -- Role of platelets -- Role of platelet-leukocyte interactions -- | |
| 505 | 8 | |a 6. Arterial, venous, and microvascular hemostasis/thrombosis -- Venous thrombosis -- Endothelial injury -- Hypercoagulability -- Stasis -- Coexistence of Virchow's triad components: cancer and thrombosis -- Arterial thrombosis -- Microvascular thrombosis -- | |
| 505 | 8 | |a 7. Summary -- Bibliography. | |
| 506 | |a Abstract freely available; full-text restricted to subscribers or individual document purchasers. | ||
| 520 | 3 | |a Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, vascular injury or inflammation result in a coordinated series of events including platelet adhesion, aggregation, and promotion of coagulation. In this review, we describe the primary mechanisms involved in these responses in various vascular beds of both macro- and microvessels, and outline key unresolved aspects of these important interactions. | |
| 538 | |a Mode of access: World Wide Web. | ||
| 538 | |a System requirements: Adobe Acrobat reader. | ||
| 650 | 0 | |a Thrombosis. |0 http://id.loc.gov/authorities/subjects/sh85135077 | |
| 650 | 0 | |a Hemostasis. |0 http://id.loc.gov/authorities/subjects/sh85060240 | |
| 650 | 0 | |a Blood platelets. |0 http://id.loc.gov/authorities/subjects/sh85015006 | |
| 650 | 1 | 2 | |a Thrombosis. |
| 650 | 1 | 2 | |a Hemostasis. |
| 650 | 1 | 2 | |a Blood Platelets. |
| 650 | 7 | |a Blood |x Coagulation. |2 fast |0 http://id.worldcat.org/fast/fst00834568 | |
| 650 | 7 | |a Blood platelets. |2 fast |0 http://id.worldcat.org/fast/fst00834782 | |
| 700 | 1 | |a Thiagarajan, Perumal. |0 http://id.loc.gov/authorities/names/no2010082620 |1 http://viaf.org/viaf/121248244 | |
| 830 | 0 | |a Colloquium series on integrated systems physiology, from molecule to function, |x 1947-9468 ; |v # 4. | |
| 856 | 4 | 0 | |3 Abstract with links to full text |u http://www.morganclaypool.com/doi/abs/10.4199/C00007ED1V01Y201002ISP004 |
| 903 | |a HeVa | ||
| 929 | |a eresource | ||
| 999 | f | f | |i 4157fd28-df27-5637-ad77-606ac33897ad |s 915de641-3c54-5b89-b8a3-9db97c60d216 |
| 928 | |t Library of Congress classification |a RC694.3 .R856 2010 |l Online |c UC-FullText |u http://www.morganclaypool.com/doi/abs/10.4199/C00007ED1V01Y201002ISP004 |m Abstract with links to full text: |g ebooks |i 6808765 | ||