The exocrine pancreas /
Saved in:
Author / Creator: | Pandol, Stephen. |
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Imprint: | San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan & Claypool, c2011. |
Description: | 1 electronic text (viii, 56 p.) : ill., digital file. |
Language: | English |
Series: | Colloquium series in integrated systems physiology, from molecule to function, 2154-5626 ; # 14 Colloquium series on integrated systems physiology, from molecule to function, # 14. |
Subject: | |
Format: | E-Resource Book |
URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/8512946 |
ISBN: | 9781615041398 (electronic bk.) 9781615041381 (pbk.) |
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Notes: | Series from website. Includes bibliographical references (p. 45-56). Abstract freely available; full-text restricted to subscribers or individual document purchasers. System requirements: Adobe Acrobat reader. |
Summary: | The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms. |
Standard no.: | 10.4199/C00026ED1V01Y201102ISP014 |
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