The Liver : biology and pathobiology /
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| Edition: | 2nd ed. |
|---|---|
| Imprint: | New York : Raven Press, c1988. |
| Description: | xxv, 1377 p. : ill. ; 29 cm. |
| Language: | English |
| Subject: | |
| Format: | Print Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/868028 |
Table of Contents:
- Contributing Authors
- Preface
- Acknowledgments
- Part I. Introduction
- 1.. Organizational Principles
- 2.. Embryonic Development of the Liver
- Part II. The Cells
- W-1.. Biology and Pathobiology of Actin in the Liver
- W-2.. Cytoskeleton: Intermediate Filaments
- 3.. Gap and Tight Junctions in Liver: Composition, Regulation, and Function
- 4.. Motor Molecules
- W-3.. Motor Molecules of the Cytoskeleton: Possible Functions in the Hepatocyte
- 5.. Gene Regulation and In Vivo Function of Liver Transcription Factors
- 6.. The Hepatocyte Plasma Membrane: Organization, Differentiation, Biogenesis, and Turnover
- W-4.. Plasma Membrane: Biogenesis and Turnover
- 7.. Hepatocyte Basolateral Membrane Organic Anion Transporters
- 8.. The Hepatocyte Surface: Dynamic Polarity
- W-5.. Hepatocyte Surface Polarity
- 9.. The Endoplasmic Reticulum and Golgi Complex in Secretory Membrane Transport
- W-6.. The Endoplasmic Reticulum-Golgi Membrane System
- W-7.. Mechanisms of Nuclear Entry
- 10.. Molecular Mechanisms of Hepatocellular Vesicle Formation
- 11.. Receptor-Mediated Endocytosis
- 12.. Peroxisomal Assembly, Biology, and Disease Relationship
- W-8.. Peroxisomes
- W-9.. Lysosomes
- W-10.. Mitochondria
- Section A. Hepatocyte: Metabolism
- W-11.. Energy Metabolism
- 13.. Integrated Cell Function: Apoptosis
- 14.. Fundamentals of Cellular Osmoregulation
- 15.. Roles of Intracellular Proteolysis in Hepatocyte Cell-Cycle, Aging, and Programmed Cell Death
- 16.. Regulation of Hepatic Cholesterol Homeostasis
- W-12.. Lipoprotein Metabolism
- 17.. Leptin and the Liver
- 18.. Hypoxic, Ischemic, and Reperfusion Injury to Liver
- 19.. Protective Mechanisms Against Reactive Oxygen Species
- W-13.. Reactive Oxygen Species
- W-14.. Detoxication: Oxidation and Reduction
- W-15.. Detoxication: Conjugation and Hydrolysis
- 20.. Disorders of Bilirubin Metabolism
- W-16.. Heme and Bile Pigment Metabolism
- 21.. The Porphyrias
- W-17.. Heme Biosynthesis, the Porphyrias, and the Liver
- 22.. Copper Metabolism and the Liver
- W-18.. Copper and Zinc
- 23.. The Liver and Iron
- W-19.. Liver and Iron
- W-20.. Retinoid (Vitamin A) Metabolism and the Liver
- W-21.. Liver in Relation to Water-Soluble Vitamins
- Section B. Bile Secretion
- 24.. The Biology of the Bile Canaliculus
- W-22.. Bile Acids
- W-23.. Enterohepatic Circulation
- W-24.. Bile Flow
- 25.. Conjugate Export Pumps of the Multidrug Resistance Protein (MRP) Family in Liver
- 26.. Genetic Defects of Canalicular Transport
- 27.. Hormonal Regulation of Bile Secretion
- 28.. Nucleotide Transport and Regulation of Bille Formation
- 29.. The Pathobiology of Biliary Epithelia
- W-25.. The Biology of Biliary Epithelia
- Section C. Sinusoidal Cells
- 30.. Endothelial and Pit Cells
- 31.. Hepatic Stellate Cells: Morphology, Function, and Regulation
- W-26.. Kupffer and Sinusoidal Endothelial Cells
- Section D. Extracellular Matrix
- 32.. The Extracellular Matrix of the Liver
- W-27.. Extracellular Matrix
- 33.. Integrins
- W-28.. Cell-Extracellular Matrix Interactions
- Part III. Interrelated Cell Functions
- 34.. Role of Inositol Trisphosphate and Diacylglycerol in the Regulation of Liver Function
- 35.. Synthesis of and Signaling Through D-3 Phosphoinositides
- 36.. Insulin and Other Growth Factors
- W-29.. Insulin, Insulin-Like Growth Factors and Their Receptors
- 37.. Cyclic AMP Signaling in the Liver: Coupling Transcription to Physiology and Proliferation
- 38.. Ca[superscript 2+] Signaling in the Liver
- 39.. Nitric Oxide in the Liver
- 40.. Interleukin-6 Signaling During the Acute-Phase Response of the Liver
- W-30.. Leukotrienes and Other Eicosanoids in Liver Pathophysiology
- 41.. Innate Immune Sensing and the Toll-Like Receptors
- 42.. Liver Regeneration
- W-31.. Liver Regeneration
- 43.. Hepatocyte Growth Factor: Its Role in Hepatic Growth and Pathobiology
- Part IV. The Organ
- W-32.. Hepatic Microvascular System
- W-33.. Flow, Cell Entry, Metabolic Disposal, and Product Formation in the Liver
- Part V. Relation to Other Organs
- 44.. Hepatic Encephalopathy
- 45.. Alterations of the Kidney in Liver Disease
- W-34.. Kidney in Liver Disease
- W-35.. Interaction of Liver, Muscle, and Adipose Tissue in the Regulation of Metabolism in Response to Nutritional and Other Factors
- W-36.. Hypothalamic-Pituitary-Liver Axis: Growth Hormone Controls Liver Sex
- W-37.. Vitamin K-Dependent Blood Coagulation Proteins
- W-38.. Hemopoietic Functions of the Liver
- W-39.. Hepatobiliary Influences on the Skeletal System
- W-40.. Molecular Aspects of Aspects of Autoimmune Liver Disease
- Part VI. Pathobiologic Analysis
- 46.. Molecular Pathophysiology of Membrane Transport Function in Cholestasis
- 47.. The Biology of Portal Hypertension
- 48.. [alpha]1-Antitrypsin Deficiency
- 49.. Pathophysiology of Liver Fibrosis
- 50.. Alcoholic and Nonalcoholic Steatohepatitis
- W-41.. Ethanol and the Liver
- 51.. Schistosomiasis: A Model of Immunologically Mediated Liver Disease
- 52.. Immune Mechanisms of Viral Clearance and Disease Pathogenesis During Viral Hepatitis
- 53.. Epidemiology, Natural History, and Prevention of Viral Hepatitis
- 54.. Molecular Bases of Hepatitis B--and Hepatitis C--Related Chronic Liver Disease
- 55.. Molecular Biology of Hepatitis Viruses
- 56.. Liver Transplantation: Factors Affecting the Balance Between Tolerance and Rejection in Experimental Models
- W-42.. The Woodchuck Model of Hepatitis B Virus Infection
- 57.. Viral Hepatitis: Antiviral Therapy
- Part VII. Horizons
- 58.. Tissue Engineering of the Liver
- 59.. A Genomic View of Hepatology: The Example of Liver Fibrosis
- 60.. After Proteomics Comes Glycomics: How Proteins and Saccharides Interact and Influence Cell Biology
- 61.. Liver Repopulation Through Cell Transplantation
- 62.. Liver-Directed Gene Therapy
- 63.. Novel Strategies for Manipulating Hepatic Gene Expression In Vivo
- 64.. Regulation of the Eukaryotic Cell Cycle
- 65.. Molecular and Cellular Control of Angiogenesis
- 66.. Dynamics of Hepatitis B Virus Infection
- 67.. Telomeres and Telomerase in Experimental Liver Cirrhosis
- 68.. Mechanism(s) of Hepatocarcinogenesis: Insight from Transgenic Mouse Models
- 69.. Orphan Nuclear Receptors and Regulation of Cholesterol and Bile Acid Metabolism
- Subject Index
