Drug metabolism : current concepts /

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Bibliographic Details
Imprint:Dordrecht : Springer, c2005.
Description:1 online resource (x, 420 p.) : ill.
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/8875265
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Other authors / contributors:Ionescu, Corina.
Caira, Mino R.
ISBN:9781402041426
140204142X
Notes:Includes bibliographical references and index.
Description based on print version record.
Summary:Provides a comprehensive understanding of the processes that take place following ingestion of a medicinal agent or xenobiotic, with an emphasis on the crucial role of metabolism (biotransformation). This book also explains how a sound knowledge of these phenomena is incorporated into the design of effective new drug candidates.
Other form:Print version: Drug metabolism. Dordrecht : Springer, c2005 1402041411 9781402041419
Table of Contents:
  • Drug Metabolism in Context; Pathways of Biotransformation
  • Phase I Reactions; Pathways of Biotransformation
  • Phase II Reactions; Enzymatic Systems Involved in Drug Biotransformation; Induction and Inhibition of Drug-Metabolising Enzymes; Factors that Influence Drug Biotransformation; Impact of Gene Variability on Drug Metabolism; Drug Interactions and Adverse Reactions; Strategies for Drug Design.