Introduction to mathematical methods in bioinformatics /

Introduction to mathematical methods in bioinformatics /

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Bibliographic Details
Author / Creator:	Isaev, Alexander.
Imprint:	Berlin ; New York : Springer, c2004.
Description:	1 online resource (xiii, 294 p.) : ill.
Language:	English
Series:	Universitext Universitext.
Subject:	Bioinformatics -- Mathematics. Computational Biology -- methods. Models, Theoretical. Sequence Analysis -- methods.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/8877606

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ISBN:	3540219730 (alk. paper) 9783540219736 (alk. paper) 9783540484264 (electronic bk.) 3540484264 (electronic bk.) 6611350845 9786611350840
Notes:	Includes bibliographical references (p. [285]-288).
Summary:	"This book looks at the mathematical foundations of the models currently in use. This is crucial for the correct interpretation of the outputs of the models. A bioinformatician should be able not only to use software packages, but also to know the mathematics behind these packages." "From this point of view, mathematics departments throughout the world have a major role to play in bioinformatics education by teaching courses on the mathematical foundations of the subject. Based on the courses taught by the author the book combines several topics in biological sequence analysis with mathematical and statistical material required for such analysis."--Jacket.
Other form:	Print version: Isaev, Alexander. Introduction to mathematical methods in bioinformatics. Berlin ; New York : Springer, c2004 3540219730

Table of Contents:

Introduction: Biological Sequences
Sequence Alignment
Markov Chains and Hidden Markov Models
Protein Folding
Phylogenetic Reconstruction
Elements of Probability Theory
Significance of Sequence Alignment Scores
Elements of Statistics
Substitution Matrices
Exercises
Bibliography
Index