Tumor-induced immune suppression : mechanisms and therapeutic reversal /

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Bibliographic Details
Imprint:New York, NY : Springer, c2008.
Description:1 online resource (ix, 301 p.) : ill.
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/8884771
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Other authors / contributors:Gabrilovich, Dmitry I.
Hurwitz, Arthur A.
ISBN:9780387691176 (alk. paper)
0387691170
9780387691183 (e-ISBN)
0387691189 (e-ISBN)
6611216855
9786611216856
Notes:Includes bibliographical references and index.
Other form:Print version: Tumor-induced immune suppression. New York, NY : Springer, c2008 9780387691176 0387691170
Table of Contents:
  • Introduction
  • Mechanisms and Therapeutic Reversal of the Defects in T-Cell Function in Cancer
  • Molecular Mechanisms of Tumor-Associated T-Cell Tolerance
  • T-Cell Tolerance
  • T-Cell Inhibitory Molecules and Suppression of T-Cell Function In Cancer
  • CTLA-4 and T-Cell Tolerance in Cancer
  • Regulatory T-Cells in Cancer
  • T-Cell Apoptosis in Cancer
  • Defects in Dendritic Cell Differentiation in Cancer and Tumor Escape
  • Dendritic Cells With Tolerogenic Potential in Cancer
  • Signaling Pathways in Antigen-Presenting Cells Involved in Induction of T-Cell Tolerance
  • Macrophages and Tumor Development
  • Immature Myeloid Suppressor Cells in Tumor-Induced T-Cell Tolerance
  • Arginin Metabolism as A Critical Element of Tumor Suppression in Cancer
  • Role of Reactive Oxygen Species in T-Cell Defects in Cancer
  • Cytokine Production in Cancer and their Negative Effect on Immune Response
  • Inflammation and Immune Abnormalities in Cancer
  • Tumor Stroma and Antitumor Immune Response
  • Tumor Associated Immune Defects. Where are Now and Where are We Going