Molecular basis for therapy of AIDS-defining cancers /
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| Imprint: | New York : Springer, c2010. |
|---|---|
| Description: | 1 online resource (xiii, 256 p.) : ill. |
| Language: | English |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/8893136 |
Table of Contents:
- Cover13;
- Foreword
- Contents
- Contributors
- The Epidemiology of Cancer in People with HIV
- Kaposis Sarcoma
- Kaposi's Sarcoma in the Pre-HAART Era
- Kaposi's Sarcoma in the HAART Era
- Non-Hodgkin Lymphoma
- HIV-Associated NHL Since the Introduction of HAART
- Cervical Cancer
- Anal Cancer
- Hodgkin Lymphoma
- HPV-Related Anogenital and Head and Neck Cancers
- Conjunctival Cancer
- Liver Cancer
- Lung Cancer
- Non-melanoma Skin Cancer
- Conclusion
- References
- Epidemiology and Clinical Characteristicsof Non-AIDS-Defining Malignancies
- Introduction
- Epidemiology
- Studies Comparing the Pre-HAART Era and the HAART Era
- Studies Linking Risk of Cancer to Level of Immunosuppression
- The Effect of Interrupted Antiretroviral Therapy on the Risk of Cancers
- Meta-analysis Comparing HIV-Infected Individuals to Solid Organ Transplant Recipients
- Hodgkin Disease
- Clinical Presentation of HL
- Treatment of HL
- Chemotherapy and HAART
- Anal Cancer
- Clinical Features of Anal Cancer
- Anal Cancer Treatment and Outcomes
- Screening for Anal Cancer
- Effect of HAART on Anal Dysplasia
- Lung Cancer
- The Effect of HAART on the Incidence of Lung Cancer
- Contribution of Smoking Tobacco to Risk of HIV-Related Lung Cancer
- Clinical Characteristics of HIV-Positive Patients with Lung Cancer
- Treatment and Outcomes of Lung Cancer in the HAART Era
- Conclusions
- References
- HIV-Related Cancer Management in Resource-Limited Settings: A Case Study of Malawi
- Overview of Malawi Health-Care System
- HIV in Malawi
- Cancer in Malawi
- Surveillance
- HIV-Related Malignancies in Malawi
- Prevention and Early Detection
- Treatment and Management
- Treatment
- Palliative Care
- Treatment of Common HIV-Related Malignancies in Malawi
- Strategies for Improving HIV-Related Malignancy Care
- Surveillance
- Prevention
- Treatment
- Training
- Partnerships
- Research
- Summary
- References
- Immunology of HIV-Associated Kaposi Sarcoma
- Introduction
- Immunity and Cancer
- Murine Models
- Evidence for the Role of Immunity in Cancer Surveillance in Humans
- Kaposi Sarcoma
- Impact of HIV-Related Immunodeficiency on the Development of KS
- Other Factors Affecting KS Risk
- Host Factors
- Environmental Factors
- Viral Factors
- Highly Active Antiretroviral Therapy (HAART) and Immune Reconstitution
- Quantitative and Qualitative HAART-Associated Immune Reconstitution
- HAART and KS
- HAART-Associated Anti-HHV-8 Immune Reconstitution
- HAART Effects on KS Independent of Anti-HHV-8 Immune Reconstitution
- KS Development and Persistence Despite HAART
- Immune Reconstitution Inflammatory Syndrome (IRIS)
- IRIS and Cancer
- Conclusion
- References
- Targeting Signal Transduction Pathways for the Treatment of Kaposi Sarcoma
- Introduction
- Biology of Kaposi Sarcoma
- Therapeutic Opportunities
- Summary
- References
- Role of NF-B Inhibitors in HIV-Related Malignancies
- The NF-B Pathway Is Central to Cell Survival
- NF-B in Cancer
- HIV/AIDS and Malignancies
- NF-B in AIDS-Associated Viral Oncogenesis
- Gamma Herpesviruses and NF-B
- Murine Gamma Herpesvirus 68 (MHV-68)
- Kaposis Sarc.