Adverse drug reactions /
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| Imprint: | Heidelberg : Springer, c2010. |
|---|---|
| Description: | 1 online resource (x, 556 p.) : ill. |
| Language: | English |
| Series: | Handbook of experimental pharmacology, 1865-0325 ; vol. 196 Handbook of experimental pharmacology ; v. 196. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/8896045 |
Table of Contents:
- Target organ toxicity. Drug-induced liver injury / Michael Holt, Cynthia Ju
- Drug herpersensitivity reactions involving skin / Oliver Hausmann, Benno Schnyder, Werner J. Pichler
- Adverse drug reactions affecting blood cells / Richard H. Aster
- Molecular mechanisms of adverse drug reactions in cardiac tissue / Reza Tabrizchi
- Mechanisms of drug-induced nephrotoxicity / Thomas D. Nolin, Jonathan Himmelfarb
- Receptor- and reactive intermediate-mediated mechanisms of teratogenesis / Peter G. Wells ... [et al.]
- Mediators/biochemical pathways. Role of reactive metabolites in drug-induced hepatotoxicity / A.M. Srivastava ... [et al.]
- Role of cytokines in the mechanism of adverse drug reactions / Mary Jane Masson, Lindsay A. Collins, Lance R. Poh
- Keap1-Nrf2 cellular defense pathway: mechanisms of regulation and role in protection against drug-induced toxicity / Ian M. Copple ... [et al.]
- Signal transduction pathways involved in drug-induced liver injury / Derick Han ... [et al.]
- Mictrochondrial involvement in drug-induced liver injury / Dominique Pessayre ... [et al.]
- Examples/Models. Mechanisms of acetaminophen-induced liver necrosis / Jack A. Hinson, Dean W. Roberts, Laura P. James
- Drug-induced liver injury in humans: the case of Ximelagtran / M. Keisu, T.B. Andersson
- Troglitazone / Tsuyoshi Yokoi
- Neviropine hypersensitivity / M. Popovic ... [et al.]
- Mechanisms of adverse drug reactions to biologics / Janet B. Clarke
- Risk factors/screening drug candidates. Pharmacogenetics of idiosyncratic adverse drug reactions / Munir Pirmohamed
- Danger hypothesis applied to idiosyncratic drug reactions / Jinze Li, Jack P. Uetrecht
- Approaches for minimizing metabolic activation of new drug candidates in drug discovery / Sanjeev Kumar ... [et al.].