Mass spectrometry for drug discovery and drug development /

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Bibliographic Details
Imprint:Hoboken, N.J. : John Wiley & Sons, c2013.
Description:1 online resource.
Language:English
Series:Wiley series on mass spectrometry
Wiley-Interscience series on mass spectrometry.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/9040647
Hidden Bibliographic Details
Other authors / contributors:Korfmacher, Walter A.
ISBN:9781118516126 (electronic bk.)
1118516125 (electronic bk.)
9780470942383 (cloth)
047094238X (cloth)
Notes:Includes bibliographical references and index.
Description based on print version record.
Other form:Original 9780470942383 047094238X
Table of Contents:
  • 1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / GeĢrard Hopfgartner
  • 2. Utility of high-resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang
  • 3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia
  • 4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou
  • 5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash
  • 6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky
  • 7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak
  • 8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion
  • 9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendra N. Pramanik
  • 10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli
  • 11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer
  • 12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury
  • 13. Mass spectrometry of siRNA / Mark T. Cancilla and W. Michael Flanagan
  • 14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily
  • 15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high-resolution full scan? / Lieve Dillen and Filip Cuyckens.