Immunomic discovery of adjuvants and candidate subunit vaccines /

Immunomic discovery of adjuvants and candidate subunit vaccines /

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Bibliographic Details
Imprint:	New York : Springer, c2013.
Description:	1 online resource.
Language:	English
Series:	Immunomics reviews ; 5
Subject:	Vaccines. Adjuvants, Immunologic. Antigens. Vaccines -- pharmacology -- history. Vaccines. Immunological adjuvants. Antigens. Vaccines -- Design -- History. History.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/9848980

Hidden Bibliographic Details
Other authors / contributors:	Flower, Darren R. Perrie, Yvonne.
ISBN:	9781461450702 (electronic bk.) 1461450705 (electronic bk.) 9781461450696
Notes:	Description based on print version record.
Summary:	Vaccine discovery is one of the most exciting and fast-moving areas of applied science. Since Edward Jenner's work in the 18th century, vaccines have transformed health across the globe. Bringing together clinical, experimental, and computational disciplines vaccinology addresses the most pressing needs of 21st century health-care: the great infectious diseases threatening the developing world, such as HIV, Malaria, and TB; and chronic diseases, such as dementia, threatening the developed world. This volume seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology.
Other form:	Print version: Immunomic discovery of adjuvants and candidate subunit vaccines. New York ; London : Springer, 2012 9781461450696

Description
Summary:	This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.
Physical Description:	1 online resource.
ISBN:	9781461450702 (electronic bk.) 1461450705 (electronic bk.) 9781461450696