Experimental and clinical metastasis : a comprehensive review /

Experimental and clinical metastasis : a comprehensive review /

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Bibliographic Details
Imprint:New York ; London : Springer, 2013.
Description:1 online resource.
Language:English
Subject:
Neoplasm Metastasis.
Lymphatic Metastasis.
Metastasis.
Metastasis.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/9849486
Hidden Bibliographic Details
Other authors / contributors:Burnier, Julia V.
Burnier, Miguel N.
ISBN:9781461436850 (electronic bk.)
1461436850 (electronic bk.)
9781461436843
Notes:Includes index.
Description based on print version record.
Summary:The primary cause of death related to cancers can be traced back to metastases, originated from cancer cells. The presence of metastatic disease, the spread of cancer cells, is the most important prognostic and survival factor in patients with cancer. Although treatment of the primary tumor is well established and usually results in local control, treating metastatic disease is a much more daunting task. At diagnosis, few patients present with clinically detectable metastatic lesions regardless of the clinical prognostic factor. Clinical trials assessing potential therapeutic agents are important in order to define the best specific treatment for a particular patient, which are the basis for patient-oriented research that eventually lead to personalized medicine.This volume aims to comprehensively present the latest research and information about metastasis. Understanding the mechanisms underlying the metastatic phenomenon could have vast implications for the large number of patients who are at a high risk for the development of metastasis.
Other form:Print version: Experimental and clinical metastasis. New York ; London : Springer, 2012 9781461436843
Table of Contents:
  • Introduction to Metastatic Diseases
  • Introduction / Julia V. Burnier, Miguel N. Burnier Jr.
  • Interactions of Normal Tissues and Systems with Metastatic Cells: Impact on Location, Survival and Growth / Jennifer M Kirstein, Ann F. Chambers-- Gene properties of Metastatic CellsFinalRE
  • Introduction to Metastasis Suppressor Genes / Jean-Claude Marshall, Silvin Bakalian
  • Metastasis Suppressor Genes / Jean-Claude Marshall, Silvin Bakalian
  • Metastatic Dormancy and Metastasis Suppressor Genes / Jean-Claude Marshall, Silvin Bakalian
  • Clinical Implications / Jean-Claude Marshall, Silvin Bakalian, Claudia Maria de Oliveira Martins
  • IMolecular Mechanisms of Tumor Growth and Spread
  • Cell Cycle Control and Growth Factor Systems in Metastasis / Jonathan Cools-LartigueJonathan Spicer
  • Regulation of Angiogenesis by Tumour Suppressor Pathways / Karen J. Lefebvre, Sarah Assadian, Wissal El-Assaad, Jose G. Teodoro
  • Inflammatory Mediators in Tumorigenesis and Metastasis / Jeremy Dupaul-Chicoine, Maya Saleh
  • Role of Stroma in Disease Progression / Nicholas R. Bertos, Morag Park
  • Methods of Tumor Dissemination
  • Local Invasion / Patricia Rusa Pereira
  • Lymphatic Dissemination / Alexandre Nakao Odashiro
  • Hematogenous Dissemination / Bruno F. Fernandes
  • Other Methods of Tumor Dissemination / Abelardo A. Rodríguez-Reyes
  • Animal Models of Metastasis
  • Haematogenous Models of Metastases / Patrick T. Logan
  • Spontaneous, Induced, and Transgenic Models of Metastasis / Patrick T. Logan
  • Orthotopic and Ectopic Models of Metastasis / William J. Muller, Ian Swanson
  • Animal Model Imaging Techniques / Patrick T. Logan
  • Diagnosis and Treatment of Metastatic Disease
  • Diagnosis of Metastasis / Dawn Russell-Hermanns
  • Cancer Staging / Alexandre Nakao Odashiro.

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