Hepatitis C virus : from molecular virology to antiviral therapy /
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| Imprint: | Berlin ; London : Springer, 2013. |
|---|---|
| Description: | 1 online resource. |
| Language: | English |
| Series: | Current topics in microbiology and immunology ; 369 Current topics in microbiology and immunology ; 1020. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/9850210 |
MARC
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| 245 | 0 | 0 | |a Hepatitis C virus : |b from molecular virology to antiviral therapy / |c edited by Ralf Bartenschlager. |
| 260 | |a Berlin ; |a London : |b Springer, |c 2013. | ||
| 300 | |a 1 online resource. | ||
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| 490 | 1 | |a Current topics in microbiology and immunology ; |v 369 | |
| 505 | 0 | 0 | |t The Origin of Hepatitis C Virus / |r Peter Simmonds -- |t Cell Culture Systems for Hepatitis C Virus / |r Eike Steinmann, Thomas Pietschmann -- |t Animal Models for Hepatitis C / |r Eva Billerbeck, Ype de Jong, Marcus Dorner -- |t Hepatitis C Virus Entry / |r Mirjam B. Zeisel, Daniel J. Felmlee -- |t Hepatitis C Virus Proteins: From Structure to Function / |r Darius Moradpour, François Penin -- |t Hepatitis C Virus RNA Translation / |r Michael Niepmann -- |t Hepatitis C Virus RNA Replication / |r Volker Lohmann -- |t Virion Assembly and Release / |r Brett D. Lindenbach -- |t Innate Immune Responses to Hepatitis C Virus / |r John W. Schoggins, Charles M. Rice -- |t Adaptive Immune Responses in Hepatitis C Virus Infection / |r Christoph Neumann-Haefelin, Robert Thimme -- |t Liver Injury and Disease Pathogenesis in Chronic Hepatitis C / |r Daisuke Yamane, David R. McGivern -- |t Hepatitis C Virus-Specific Directly Acting Antiviral Drugs / |r Leen Delang, Johan Neyts, Inge Vliegen -- |t Treatment of Chronic Hepatitis C: Current and Future / |r Jean-Michel Pawlotsky. |
| 588 | |a Description based on print version record. | ||
| 520 | |a Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted. | ||
| 650 | 1 | 2 | |a Hepacivirus. |
| 650 | 0 | |a Hepatitis C virus. |0 http://id.loc.gov/authorities/subjects/sh94002666 | |
| 655 | 4 | |a Electronic books. | |
| 650 | 7 | |a Hepatitis C virus. |2 fast |0 http://id.worldcat.org/fast/fst00955217 | |
| 700 | 1 | |a Bartenschlager, Ralf. |0 http://id.loc.gov/authorities/names/nb2008027383 |1 http://viaf.org/viaf/58614935 | |
| 776 | 0 | 8 | |i Print version: |t Hepatitis C virus. |d Berlin ; London : Springer, 2013 |z 9783642273391 |w (OCoLC)821703422 |
| 830 | 0 | |a Current topics in microbiology and immunology ; |v 1020. | |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1007/978-3-642-27340-7 |y SpringerLink |
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| 928 | |t Library of Congress classification |a QR201.H46 H47 2013 |l Online |c UC-FullText |u http://dx.doi.org/10.1007/978-3-642-27340-7 |z SpringerLink |g ebooks |i 11492240 | ||