Extracellular matrix in development /

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Bibliographic Details
Imprint:	Berlin ; New York : Springer, c2013.
Description:	1 online resource.
Language:	English
Series:	Biology of extracellular matrix, 0887-3224 Biology of extracellular matrix (Springer (Firm))
Subject:	Extracellular matrix. Developmental biology. Developmental biology. Extracellular matrix. Extracellular Matrix. Developmental Biology.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/9850329

Hidden Bibliographic Details
Other authors / contributors:	DeSimone, Douglas W. Mecham, Robert P.
ISBN:	9783642359354 (electronic bk.) 3642359353 (electronic bk.) 9783642359347
Notes:	Includes index.
Summary:	Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix - secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Table of Contents:

Part I. Informational Signals in Extracellular Matrix and Matrix Influences on Cell Movement in the Developing Embryo. The Glycocode: Translating Heparan Sulfate Fine Structure into Developmental Function / Adam B. Cadwallader, H. Joseph Yost
Extracellular Matrix Dynamics in Early Development / Andras Czirok, Brenda J. Rongish, Charles D. Little
Extracellular Matrix Functions in Amphibian Gastrulation / Bette J. Dzamba, Douglas W. DeSimone
Part II. Extracellular Matrix-Direct Morphogenesis, Growth Factor Signaling, and Maintenance of the Stem Cell Niche. Cell-ECM Interactions and the Regulation of Epithelial Branching Morphogenesis / William P. Daley, Kenneth M. Yamada
Interactions Between Neural Crest-Derived Cells and Extracellular Microenvironment During Cardiovascular Development / Sophie Astrof
Engineered ECM Microenvironments and Their Regulation of Stem Cells / Yu Suk Choi, Andrew W. Holle, Adam J. Engler
Part III. Model Organisms and the Lexicon of Developmental Signals Associated with the Extracellular Matrix. ECM in Hydra Development and Regeneration / Xiaoming Zhang, Michael P. Sarras Jr
Extracellular Matrix Remodeling in Zebrafish Development / Nathan A. Mundell, Jason R. Jessen
The Role of HA and Has2 in the Development and Function of the Skeleton / Peter J. Roughley, Pierre Moffatt.

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