Spotlight on familial and hereditary gastric cancer /

Spotlight on familial and hereditary gastric cancer /

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Bibliographic Details
Imprint:Dordrecht ; New York : Springer, c2013.
Description:1 online resource : col. ill.
Language:English
Subject:
Stomach Neoplasms -- genetics.
Stomach -- Cancer -- Genetic aspects.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/9851384
Hidden Bibliographic Details
Other authors / contributors:Corso, Giovanni.
Roviello, Franco.
ISBN:9789400765702 (electronic bk.)
9400765703 (electronic bk.)
9789400765696
Notes:Includes bibliographical references and index.
Summary:In this book we have taken a comprehensive look at the subject of familial and hereditary gastric tumors. In particular, the aim of this novel editorial work is to propose the correct management of hereditary diffuse gastric cancer patients, focusing in particular on E-cadherin germline mutations, clinical criteria definition, genetic screening and molecular mechanisms, pathology and microscopic features, surgical treatment and clinical approach for asymptomatic mutation carriers. We also describe other inherited predispositions involving gastric carcinoma.
Table of Contents:
  • General Issues. Historical Overview of Familial Gastric Cancer / Giovanni Corso
  • Frequency of Familial Gastric Cancer / Giovanni Corso, Daniele Marrelli
  • The Family Cancer Database / Giovanni Corso, Daniele Marrelli, Franco Roviello
  • Genetics and Epigenetics. The E-Cadherin Gene, Structure and Function / Francesco Graziano
  • E-Cadherin Germline Mutations / Joana Carvalho, Hugo Pinheiro, Carla Oliveira
  • Molecular Mechanisms of Hereditary Diffuse Gastric Cancer Initiation and Progression / Parry Guilford, Bostjan Humar
  • Germline Missense Mutants in Hereditary Diffuse Gastric Cancer / Joana Figueiredo, Raquel Seruca
  • Alternative Mechanisms to Germline CDH1 Mutations in Hereditary Diffuse Gastric Cancer / Hugo Pinheiro, Joana Carvalho, Carla Oliveira
  • Beyond CDH1 Mutations: Causes of Hereditary Diffuse Gastric Cancer / Samantha Hansford B.Sc., David Huntsman, FRCPC
  • Non-CDH1-Associated Familial Gastric Cancer and Epigenetics Factors / Marina Leite, Giovanni Corso, Sónia Sousa, Joana Carvalho
  • Pathology. Hereditary Diffuse Gastric Cancer and Lobular Breast Carcinoma / Gisela Keller
  • Pathology of Hereditary Gastric Cancer / Fátima Carneiro
  • Management. Clinical Criteria for Familial Gastric Cancer Definition / Giulia De Falco, Alessandro Davide Videtta
  • Prophylactic Total Gastrectomy in CDH1 Germline Mutation Carriers / Francesco Ferrara, Giovanni Corso, Franco Roviello
  • Gastric Cancer in Other Inherited Syndromes / Giovanni Corso, Sérgia Velho
  • Clinical Management of Familial Gastric Cancer / Giovanni Corso, Daniele Marrelli, Franco Roviello
  • Appendix / Giovanni Corso

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