G Protein-coupled receptors-- Modeling and simulation /

Saved in:

Bibliographic Details
Imprint:	Dordrecht : Springer, ©2014.
Description:	1 online resource (228 pages).
Language:	English
Series:	Advances in Experimental Medicine and Biology, 0065-2598 796 Advances in experimental medicine and biology ; v. 796.
Subject:	G proteins -- Receptors. G proteins -- Receptors. Receptors, G-Protein-Coupled.
Format:	E-Resource Book
URL for this record:	http://pi.lib.uchicago.edu/1001/cat/bib/11081653

Hidden Bibliographic Details
Other authors / contributors:	Filizola, Marta.
ISBN:	9789400774230 9400774230 9789400774223
Notes:	Includes index. Print version record.
Summary:	G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses. Since GPCRs are natural targets for approximately 40% of all modern medicines, it is not surprising that they have been the subject of intense research. Notwithstanding the amount of data generated over the years, discovering ligands of these receptors with optimal therapeutic properties is not straightforward and has certainly been hampered for years by the lack of high-resolution structural information about these receptors.
Other form:	Print version: 9789400774223

Similar Items