Hidden Bibliographic Details
| Other authors / contributors: | Boehm, Thomas, 1956- (Thomas L. J.), editor.
Takahama, Yousuke, editor.
|
|---|
| ISBN: | 9783642402524
3642402526
9783642402517
3642402518
9783642402517
|
|---|
| Notes: | Includes index.
Includes bibliographical references and index.
Online resource; title from PDF title page (SpringerLink, viewed November 11, 2013).
|
|---|
| Summary: | The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
|
|---|
| Standard no.: | 10.1007/978-3-642-40252-4
|
|---|
