Thymic development and selection of T Lymphocytes /
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| Imprint: | Heidelberg : Springer, 2014. |
|---|---|
| Description: | 1 online resource (vii, 132 pages) : illustrations (some color). |
| Language: | English |
| Series: | Current Topics in Microbiology and Immunology, 0070-217X ; volume 373 Current topics in microbiology and immunology ; v.373. |
| Subject: | |
| Format: | E-Resource Book |
| URL for this record: | http://pi.lib.uchicago.edu/1001/cat/bib/11082182 |
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| 245 | 0 | 0 | |a Thymic development and selection of T Lymphocytes / |c Thomas Boehm, Yousuke Takahama, editors. |
| 264 | 1 | |a Heidelberg : |b Springer, |c 2014. | |
| 300 | |a 1 online resource (vii, 132 pages) : |b illustrations (some color). | ||
| 336 | |a text |b txt |2 rdacontent |0 http://id.loc.gov/vocabulary/contentTypes/txt | ||
| 337 | |a computer |b c |2 rdamedia |0 http://id.loc.gov/vocabulary/mediaTypes/c | ||
| 338 | |a online resource |b cr |2 rdacarrier |0 http://id.loc.gov/vocabulary/carriers/cr | ||
| 490 | 1 | |a Current Topics in Microbiology and Immunology, |x 0070-217X ; |v volume 373 | |
| 505 | 0 | 0 | |t Development and Function of Cortical Thymic Epithelial Cells / |r Kensuke Takada, Izumi Ohigashi, Michiyuki Kasai, Hiroshi Nakase and Yousuke Takahama -- |t Mechanisms of Thymus Medulla Development and Function / |r Graham Anderson, Song Baik, Jennifer E. Cowan, Amanda M. Holland, Nicholas I. McCarthy [and 6 others] -- |t Self-Peptides in TCR Repertoire Selection and Peripheral T Cell Function / |r Wan-Lin Lo and Paul M. Allen -- |t Central Tolerance Induction / |r Maria L. Mouchess and Mark Anderson -- |t Trafficking to the Thymus / |r Shirley L. Zhang and Avinash Bhandoola -- |t The CD4/CD8 Lineages: Central Decisions and Peripheral Modifications for T Lymphocytes / |r Hirokazu Tanaka and Ichiro Taniuchi. |
| 500 | |a Includes index. | ||
| 520 | |a The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity. | ||
| 588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed November 11, 2013). | |
| 504 | |a Includes bibliographical references and index. | ||
| 650 | 0 | |a T cells. |0 http://id.loc.gov/authorities/subjects/sh85131766 | |
| 650 | 0 | |a Thymus |x Growth. | |
| 650 | 1 | 4 | |a Biomedicine. |
| 650 | 2 | 4 | |a Immunology. |
| 650 | 2 | 4 | |a Cytogenetics. |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 2 | |a T-Lymphocytes |x immunology. | |
| 655 | 4 | |a Electronic books. | |
| 655 | 0 | |a Electronic books. | |
| 650 | 7 | |a T cells. |2 fast |0 http://id.worldcat.org/fast/fst01141544 | |
| 700 | 1 | |a Boehm, Thomas, |d 1956- |q (Thomas L. J.), |e editor. |0 http://id.loc.gov/authorities/names/n85028638 | |
| 700 | 1 | |a Takahama, Yousuke, |e editor. |0 http://id.loc.gov/authorities/names/nb2014002073 |1 http://viaf.org/viaf/306277541 | |
| 830 | 0 | |a Current topics in microbiology and immunology ; |v v.373. |x 0070-217X | |
| 856 | 4 | 0 | |u http://link.springer.com/10.1007/978-3-642-40252-4 |y SpringerLink |
| 903 | |a HeVa | ||
| 929 | |a eresource | ||
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