Systems analysis of human multigene disorders /

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Bibliographic Details
Imprint:New York : Springer, 2014.
Description:1 online resource (134 pages) : illustrations.
Language:English
Series:Advances in Experimental Medicine and Biology ; 799
Advances in experimental medicine and biology ; v. 799.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11082694
Hidden Bibliographic Details
Other authors / contributors:Maltsev, Natalia, editor.
Rzhet︠s︡kiĭ, A. I︠U︡. (Andreĭ I︠U︡rʹevich), editor.
Gilliam, T. Conrad, editor.
ISBN:9781461487784
1461487781
1461487773
9781461487777
9781461487777
Digital file characteristics:text file PDF
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (ebrary, viewed January 5, 2014).
Summary:Understanding the genetic architecture underlying complex multigene disorders is one of the major goals of human genetics in the upcoming decades. Advances in whole genome sequencing and the success of high throughput functional genomics allow supplementing conventional reductionist biology with systems-level approaches to human heredity and health as systems of interacting genetic, epigenetic, and environmental factors. This integrative approach holds the promise of unveiling yet unexplored levels of molecular organization and biological complexity. It may also hold the key to deciphering the multigene patterns of disease inheritance.
Other form:Printed edition: 9781461487777
Standard no.:10.1007/978-1-4614-8778-4