Hidden Bibliographic Details
| Other authors / contributors: | Hammarlund-Udenaes, Margareta.
Lange, Elizabeth C. M. de
Thorne, Robert G.
|
|---|
| ISBN: | 9781461491057
1461491053
1461491045
9781461491040
9781461491040
|
|---|
| Digital file characteristics: | text file PDF
|
|---|
| Notes: | Includes bibliographical references and index.
Online resource; title from PDF title page (ebrary, viewed January 2, 2014).
|
|---|
| Summary: | The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood -brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma.
|
|---|
| Other form: | Print version: Drug delivery to the brain. New York : Springer Science+Business Media, 2013 9781461491040 1461491045
|
|---|
| Standard no.: | 10.1007/978-1-4614-9105-7
|
|---|
