Tumor-induced immune suppression : mechanisms and therapeutic reversal /

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Bibliographic Details
Edition:Second edition.
Imprint:New York, NY : Springer, [2014]
©2014
Description:1 online resource (ix, 301 pages) : illustrations
Language:English
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11083391
Hidden Bibliographic Details
Other authors / contributors:Gabrilovich, Dmitry I., editor.
Hurwitz, Arthur A., editor.
ISBN:9781489980564
1489980563
1489980555
9781489980557
9781489980557
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (SpringerLink, viewed Feb. 21, 2014).
Summary:Tumor-Induced Immune Suppression - Prospects and Progress in Mechanisms and Therapeutic Reversal presents a comprehensive overview of large number of different mechanisms of immune dysfunction in cancer and therapeutic approaches to their correction. This includes the number of novel mechanisms that has never before been discussed in previous monographs. The last decades were characterized by substantial progress in the understanding of the role of the immune system in tumor progression. Researchers have learned how to manipulate the immune system to generate tumor specific immune response, which raises high expectations for immunotherapy to provide breakthroughs in cancer treatment. It is increasingly clear that tumor-induced abnormalities in the immune system not only hampers natural tumor immune surveillance, but also limits the effect of cancer immunotherapy. Therefore, it is critically important to understand the mechanisms of tumor-induced immune suppression to make any progress in the field and this monograph provides these important insights.
Other form:Printed edition: 9781489980557
Standard no.:10.1007/978-1-4899-8056-4