Hidden Bibliographic Details
Other authors / contributors: | Fillatreau, Simon, editor.
O'Gara, Anne, editor.
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ISBN: | 9783662434925 366243492X 3662434911 9783662434918 9783662434918
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Notes: | Includes bibliographical references and index. Online resource; title from PDF title page (Ebsco, viewed July 18, 2014).
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Summary: | This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.
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Other form: | Printed edition: 9783662434918
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Standard no.: | 10.1007/978-3-662-43492-5
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