Interleukin-10 in health and disease /

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Bibliographic Details
Imprint:Berlin : Springer Verlag, [2014]
Description:1 online resource.
Language:English
Series:Current topics in microbiology and immunology ; Volume 380
Current topics in microbiology and immunology ; 380.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11086375
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Other authors / contributors:Fillatreau, Simon, editor.
O'Gara, Anne, editor.
ISBN:9783662434925
366243492X
3662434911
9783662434918
9783662434918
Notes:Includes bibliographical references and index.
Online resource; title from PDF title page (Ebsco, viewed July 18, 2014).
Summary:This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.
Other form:Printed edition: 9783662434918
Standard no.:10.1007/978-3-662-43492-5