Fc receptors /

Fc receptors /

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Bibliographic Details
Imprint:Cham : Springer, [2014]
©2014
Description:1 online resource.
Language:English
Series:Current topics in microbiology and immunology ; volume 382
Current topics in microbiology and immunology ; v. 382.
Subject:
Fc receptors.
Fc receptors.
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11087093
Hidden Bibliographic Details
Other authors / contributors:Daëron, M. (Marc), editor.
Nimmerjahn, Falk, editor.
ISBN:9783319079110
3319079115
9783319079103
3319079107
Notes:Includes bibliographical references and index.
Print version record.
Summary:This volume provides a state-of-the-art update on Fc Receptors (FcRs). It is divided into five parts. Part I, Old and New FcRs, deals with the long-sought-after Fc[micro]R and the recently discovered FCRL family and TRIM21. Part II, FcR Signaling, presents a computational model of Fc[epsilon]RI signaling, novel calcium channels, and the lipid phosphatase SHIP1. Part III, FcR Biology, addresses major physiological functions of FcRs, their glycosylation, how they induce and regulate both adaptive immune responses and inflammation, especially in vivo, FcR humanized mice, and the multifaceted properties of FcRn. Part IV, FcRs and Disease, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection. In Part V, FcRs and Therapeutic Antibodies, the roles of various FcRs, including FcgRIIB and FcbRI, in the immunotherapy of cancer and autoimmune diseases using monoclonal antibodies and IVIg are highlighted. All 18 chapters were written by respected experts in their fields, offering an invaluable reference source for scientists and clinicians interested in FcRs and how to better master antibodies for therapeutic purposes.
Other form:Print version: Fc receptors 3319079107
Standard no.:10.1007/978-3-319-07911-0

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