Homology modeling : methods and protocols /

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Bibliographic Details
Imprint:New York : Humana Press, ©2012.
Description:1 online resource (xi, 419 pages)
Language:English
Series:Methods in molecular biology, 1064-3745 ; 857
Methods in molecular biology ; 857.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11125294
Hidden Bibliographic Details
Other authors / contributors:Orry, Andrew J. W.
Abagyan, Ruben.
ISBN:9781617795886
1617795887
1617795879
9781617795879
9781617795879
Digital file characteristics:text file
PDF
Notes:Includes index.
Includes bibliographical references and index.
English.
Summary:Knowledge about protein tertiary structure can guide experiments, assist in the understanding of structure-function relationships, and aid the design of new therapeutics for disease. Homology modeling is an in silico method that predicts the tertiary structure of an amino acid sequence based on a homologous experimentally determined structure. In, Homology Modeling: Methods and Protocols experts in the field describe each homology modeling step from first principles, provide case studies for challenging modeling targets and describe methods for the prediction of how other molecules such as drugs can interact with the protein. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Homology Modeling: Methods and Protocols guides scientists in the available homology modeling methods.
Other form:Printed edition: 9781617795879
Standard no.:10.1007/978-1-61779-588-6