Protein structure prediction : methods and protocols /

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Bibliographic Details
Imprint:Totowa, N.J. : Humana Press, ©2000.
Description:1 online resource (x, 422 pages) : illustrations
Language:English
Series:Methods in molecular biology ; 143
Methods in molecular biology (Clifton, N.J.) ; v. 143.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11128941
Hidden Bibliographic Details
Other authors / contributors:Webster, David M.
ISBN:1592593682
9781592593682
0896036375
9780896036376
1280842474
9781280842474
9786610842476
6610842477
Notes:Includes bibliographical references and index.
English.
Print version record.
Summary:The deeper understanding of protein structure now emerging from cutting-edge research is not only illuminating evolutionary and biochemical mechanisms, but also promises enormous ramifications for molecular medicine, as well as for biotechnology, biophysics, biology, genetics, and other molecular sciences. In Protein Structure Prediction: Methods and Protocols, world-class investigators detail their most successful methods-and the theory behind them-for delineating the shape, form, and function of proteins. The protocols range from basic to advanced and include sequence alignment, the prediction of transmembrane protein structure, and the development of suitable folding potentials. There are also techniques for receptor site prediction, the identification of motifs and domains, the comparative modeling of proteins, the docking of peptides and ligands, and ab initio approaches to protein loop and side-chain prediction. To ensure robust and successful experimental results, each protocol contains step-by-step instructions, as well as tips on pitfalls to avoid and how procedures may be optimized for different systems. Comprehensive, accessible, and highly practical, Protein Structure Prediction: Methods and Protocols offers protein researchers, structural biologists, and other investigators a critical synthesis of the latest research results, as well as the vital guidance needed to understand the structure and interaction of proteins and peptides.
Other form:Protein structure prediction
Standard no.:10.1385/1592593682.