Correlative light and electron microscopy /

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Bibliographic Details
Imprint:Amsterdam, Netherlands ; Boston, Mass. : Elsevier / Academic Press, ©2012.
Description:1 online resource (xix, 404 pages, [40] pages of plates) : illustrations (some color).
Language:English
Series:Methods in cell biology, 0091-679X ; v. 111
Methods in cell biology ; v. 111.
Subject:
Format: E-Resource Book
URL for this record:http://pi.lib.uchicago.edu/1001/cat/bib/11140148
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Other authors / contributors:Müller-Reichert, Thomas, 1962-
Verkade, Paul.
ISBN:9780123914385
0123914388
9780124160262
0124160263
Notes:Includes bibliographical references and index.
Summary:The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM. Covers many areas of CLEM by the best international scientists in the field. Includes a brief history and overview on CLEM methods.